Difference between revisions of "TFEB-rearranged renal cell carcinoma"

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==Microscopic==
==Microscopic==
Features:
Features:<ref name=pmid18998233>{{Cite journal  | last1 = Hora | first1 = M. | last2 = Hes | first2 = O. | last3 = Urge | first3 = T. | last4 = Eret | first4 = V. | last5 = Klecka | first5 = J. | last6 = Michal | first6 = M. | title = A distinctive translocation carcinoma of the kidney ["rosette-like forming," t(6;11), HMB45-positive renal tumor]. | journal = Int Urol Nephrol | volume = 41 | issue = 3 | pages = 553-7 | month =  | year = 2009 | doi = 10.1007/s11255-008-9495-8 | PMID = 18998233 }}</ref>
*Hyaline material between nests.
*Solid with occasional rosette-like structures.
*Large cells with clear to eosinophilic cytoplasm.
*Two cell populations:
*#Large epithelioid cells with clear to eosinophilic cytoplasm.
*#Small lymphocyte-like cells.
 
DDx:
*[[Renal cell carcinoma, unclassified]].
*[[Angiomyolipoma]] (epithelioid).


===Images===
===Images===
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*TFEB +ve (nuclear staining).
*TFEB +ve (nuclear staining).
*HMB-45 +ve<ref name=pmid24877033/> (focal<ref name=pmid12719541/>).
*HMB-45 +ve<ref name=pmid24877033/> (focal<ref name=pmid12719541/>).
*TFE3 -ve.


==Molecular==
==Molecular==
Retrieved from "https://librepathology.org/wiki/TFEB-rearranged_renal_cell_carcinoma"