Difference between revisions of "Soft tissue lesions"
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==WHO classification of soft tissue tumours== | ==WHO classification of soft tissue tumours== | ||
Morphologic grouping | ===Morphologic grouping<ref>WMSP PP.601-3.</ref>=== | ||
#Adipocytic tumours. | #Adipocytic tumours. | ||
#Fibroblastic/myofibroblastic tumours. | #Fibroblastic/myofibroblastic tumours. | ||
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#Tumours of uncertain differentiation. | #Tumours of uncertain differentiation. | ||
Biologic potential grouping | ===Biologic potential grouping<ref>WMSP PP.598-604.</ref>=== | ||
#Benign. | #Benign. | ||
#Intermediate (locally aggressive). | #Intermediate (locally aggressive). | ||
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*Vascular malformations. | *Vascular malformations. | ||
*Synovial sarcoma. | *Synovial sarcoma. | ||
==Hemangioendothelioma== | |||
*Usually benign. | |||
===Microscopic=== | |||
Features:<ref>Klatt. AOP P.23.</ref> | |||
*Well-formed thin vascular channels on a fibrous stroma - '''key feature'''. | |||
*+/-Thrombosis. | |||
*+/-Calcification. | |||
*+/-Fibrosis. | |||
*+/-Myxoid change. | |||
===IHC=== | |||
*Factor VIII +ve. | |||
==Desmoplastic fibroblastoma== | ==Desmoplastic fibroblastoma== | ||
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*Very many small capillaries or irregular shape lined with: | *Very many small capillaries or irregular shape lined with: | ||
**Atypical nuclei, pleomorphic nuclei. | **Atypical nuclei, pleomorphic nuclei. | ||
* | *Mitoses. | ||
*Cytoplasmic vacuoles. | |||
**Cells trying to form lumina - embryologic. | |||
==Rhabdomyosarcoma== | ==Rhabdomyosarcoma== | ||