Difference between revisions of "Leiomyosarcoma"
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==General== | ==General== | ||
*Poor prognosis. | *Poor prognosis. | ||
**In locally advanced/metastatic disease (arising from the uterus) the median survival is 12-14 months.<ref>{{Cite journal | last1 = Hadoux | first1 = J. | last2 = Morice | first2 = P. | last3 = Lhommé | first3 = C. | last4 = Duvillard | first4 = P. | last5 = Balleyguier | first5 = C. | last6 = Haie-Meder | first6 = C. | last7 = Gouy | first7 = S. | last8 = Uzan | first8 = C. | last9 = Mazeron | first9 = R. | title = [Uterine leiomyosarcoma: epidemiology, pathology, biology, diagnosis, prognosis and treatment]. | journal = Bull Cancer | volume = 100 | issue = 9 | pages = 903-15 | month = Sep | year = 2013 | doi = 10.1684/bdc.2013.1801 | PMID = 24004576 }}</ref> | |||
**Skin leiomyosarcoma do so well it has been proposed to no longer refer to them as ''sarcomas''.<ref name=pmid21358302/> | |||
*Do not (generally) arise from leiomyomas. | *Do not (generally) arise from leiomyomas. | ||
*Often singular, i.e. one tumour; unlike [[leiomyoma]]s (which are often multiple). | *Often singular, i.e. one tumour; unlike [[leiomyoma]]s (which are often multiple). | ||
*May be a part of [[hereditary leiomyomatosis and renal cell cancer]]. | *May be a part of [[hereditary leiomyomatosis and renal cell cancer]]. | ||
==Gross== | ==Gross== | ||
Features: | Features: | ||