Difference between revisions of "Squamous cell carcinoma of the head and neck"
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*[http://commons.wikimedia.org/wiki/File:Oral_cancer_(1)_squamous_cell_carcinoma_histopathology.jpg?uselang=de Invasive oral SCC (WC)]. | *[http://commons.wikimedia.org/wiki/File:Oral_cancer_(1)_squamous_cell_carcinoma_histopathology.jpg?uselang=de Invasive oral SCC (WC)]. | ||
==Overview of subtypes== | ===Overview of subtypes=== | ||
There are several subtypes:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2]. Accessed on: March 9, 2010.</ref> | There are several subtypes:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970297-2]. Accessed on: March 9, 2010.</ref> | ||
*Basaloid - poor prognosis, usu. diagnosed by recognition of typical SCC. | *Basaloid - poor prognosis, usu. diagnosed by recognition of typical SCC. | ||
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*Spindle cell, a common spindle cell lesion of the H&N. | *Spindle cell, a common spindle cell lesion of the H&N. | ||
===Verrucous squamous cell carcinoma=== | ====Verrucous squamous cell carcinoma==== | ||
Features: | Features: | ||
*Exophytic growth. | *Exophytic growth. | ||
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DDx: papilloma. | DDx: papilloma. | ||
===Spindle cell squamous carcinoma=== | ====Spindle cell squamous carcinoma==== | ||
*Key to diagnosis is finding a component of conventional squamous cell carcinoma. | *Key to diagnosis is finding a component of conventional squamous cell carcinoma. | ||
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*Mesenchymal neoplasm. | *Mesenchymal neoplasm. | ||
===Basaloid squamous cell carcinoma=== | ====Basaloid squamous cell carcinoma==== | ||
*May mimic ''[[adenoid cystic carcinoma]]''. | *May mimic ''[[adenoid cystic carcinoma]]''. | ||
*Classically base of tongue.<ref>URL: [http://www.biomedcentral.com/1471-2407/6/146 http://www.biomedcentral.com/1471-2407/6/146]. Accessed on: March 9, 2010.</ref> | *Classically base of tongue.<ref>URL: [http://www.biomedcentral.com/1471-2407/6/146 http://www.biomedcentral.com/1471-2407/6/146]. Accessed on: March 9, 2010.</ref> | ||
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*Neuroendocrine tumour. | *Neuroendocrine tumour. | ||
===Lymphoepithelial (squamous cell) carcinoma=== | ====Lymphoepithelial (squamous cell) carcinoma==== | ||
See ''[[nasopharyngeal carcinoma]]''. | See ''[[nasopharyngeal carcinoma]]''. | ||