Difference between revisions of "Small intestine"

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(note about IHC)
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The '''small bowel''' is a relatively well-behaved piece of machinery from the perspective of pathology.  It is uncommonly affected by malignancies.   
The '''small bowel''' is a relatively well-behaved piece of machinery from the perspective of pathology.  It is uncommonly affected by malignancies.   


==Anatomy==
==Anatomy==
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In the context of bowel obstructions and IBD, pathologists often see resected stomas (that were put in place emergently).  These specimens are usually fairly straight forward.
In the context of bowel obstructions and IBD, pathologists often see resected stomas (that were put in place emergently).  These specimens are usually fairly straight forward.
==[[Immunohistochemistry]]==
*Normal small intestine is CK20 +ve... while adenocarcinoma of the small bowel may be CK20 -ve.<ref>{{cite journal |author=Chen ZM, Wang HL |title=Alteration of cytokeratin 7 and cytokeratin 20 expression profile is uniquely associated with tumorigenesis of primary adenocarcinoma of the small intestine |journal=Am. J. Surg. Pathol. |volume=28 |issue=10 |pages=1352–9 |year=2004 |month=October |pmid=15371952 |doi= |url=}}</ref>


==Histology==
==Histology==