Difference between revisions of "Serous carcinoma of the ovary"

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*PAX2 +ve.
*PAX2 +ve.
**Usually -ve in [[malignant mesothelioma]].<ref name=pmid22498671>{{Cite journal  | last1 = Gao | first1 = FF. | last2 = Krasinskas | first2 = AM. | last3 = Chivukula | first3 = M. | title = Is PAX2 a reliable marker in differentiating diffuse malignant mesotheliomas of peritoneum from serous carcinomas of müllerian origin? | journal = Appl Immunohistochem Mol Morphol | volume = 20 | issue = 3 | pages = 272-6 | month = May | year = 2012 | doi = 10.1097/PAI.0b013e3182366531 | PMID = 22498671 }}</ref>
**Usually -ve in [[malignant mesothelioma]].<ref name=pmid22498671>{{Cite journal  | last1 = Gao | first1 = FF. | last2 = Krasinskas | first2 = AM. | last3 = Chivukula | first3 = M. | title = Is PAX2 a reliable marker in differentiating diffuse malignant mesotheliomas of peritoneum from serous carcinomas of müllerian origin? | journal = Appl Immunohistochem Mol Morphol | volume = 20 | issue = 3 | pages = 272-6 | month = May | year = 2012 | doi = 10.1097/PAI.0b013e3182366531 | PMID = 22498671 }}</ref>
==Sign out==
<pre>
A. RIGHT OVARY, BIOPSY:
- SEROUS CARCINOMA, HIGH-GRADE.
- PSAMMOMATOUS CALCIFICATIONS.
B. OMENTUM, BIOPSY:
- SEROUS CARCINOMA, HIGH-GRADE.
- PSAMMOMATOUS CALCIFICATIONS.
COMMENT:
The morphology is compatible with a serous carcinoma (prominent
nucleoli, large nuclear size variation, psammomatous calcifications).
The immunostains are that of a serous carcinoma:
POSITIVE: CK7, ER, PR (focal), CA-125, WT-1.
NEGATIVE: CK20, p53.
The ovary has multiple small tumour nodules.  The status of the opposite
ovary is unknown. The bulk of the tumour in the specimen provided is in
the omentum.
Clinical and radiologic correlation is suggested for the determination of
the primary site of this serous carcinoma.
</pre>


==See also==
==See also==
Retrieved from "https://librepathology.org/wiki/Serous_carcinoma_of_the_ovary"