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Difference between revisions of "Colorectal adenocarcinoma"
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Colorectal adenocarcinoma (view source)
Revision as of 13:19, 8 December 2013
, 13:19, 8 December 2013more
(more) Tag: Mobile edit |
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| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = other [[adenocarcinoma]]s | | LMDDx = other [[adenocarcinoma]]s, [[traditional adenoma]] esp. with high-grade dysplasia, [[sessile serrated adenoma]] with dysplasia | ||
| Stains = | | Stains = | ||
| IHC = CK20 +ve, CDX2 +ve, CK7 -ve, beta-catenin (nuclear) +ve | | IHC = CK20 +ve, CDX2 +ve, CK7 -ve, beta-catenin (nuclear) +ve | ||
| Line 15: | Line 15: | ||
| Grossing = | | Grossing = | ||
| Site = [[rectum]], [[colon]], [[cecum]], [[appendix]] | | Site = [[rectum]], [[colon]], [[cecum]], [[appendix]] | ||
| Assdx = long standing IBD ([[Crohn's disease]], [[ulcerative colitis]]) | | Assdx = long standing IBD ([[Crohn's disease]], [[ulcerative colitis]]), [[tradutional adenoma]] esp. with high-grade dysplasia, [[sessile serrated adenoma]] esp. with dysplasia | ||
| Syndromes = [[familial adenomatous polyposis]], [[Lynch syndrome]], [[Peutz-Jeghers syndrome]], [[Juvenile polyposis syndrome]], [[serrated polyposis syndrome]], [[MUTYH polyposis syndrome]], [[Cowden syndrome]] | | Syndromes = [[familial adenomatous polyposis]], [[Lynch syndrome]], [[Peutz-Jeghers syndrome]], [[Juvenile polyposis syndrome]], [[serrated polyposis syndrome]], [[MUTYH polyposis syndrome]], [[Cowden syndrome]] | ||
| Clinicalhx = | | Clinicalhx = | ||
| Line 26: | Line 26: | ||
| Prognosis = good to poor | | Prognosis = good to poor | ||
| Other = fecal occult blood test (FOBT) +ve | | Other = fecal occult blood test (FOBT) +ve | ||
| ClinDDx = [[colorectal tumours]] | | ClinDDx = [[colorectal tumours]], other causes - DDx dependent on presentation | ||
}} | }} | ||
'''Colorectal adenocarcinoma''' is very common, and a leading cause of death due to [[cancer]]. | '''Colorectal adenocarcinoma''' is very common, and a leading cause of death due to [[cancer]]. | ||