Difference between revisions of "Sinus histiocytosis"
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'''Sinus histiocytosis''' | '''Sinus histiocytosis''', abbreviated '''SH''', is a common finding in [[lymph nodes]]. | ||
It should '''not''' be confused with [[Rosai-Dorfman disease]] (also known as ''sinus histiocytosis and massive lymphadenopathy''). | |||
==General== | |||
*Benign. | |||
*Non-specific finding. | |||
==Microscopic== | |||
Features:<ref name=Ref_ILNP179>{{Ref_ILNP|179}}</ref> | |||
*Sinuses distended with histiocytes - '''key feature'''. | |||
*[[Plasma cell]]s increased. | |||
DDx: | |||
*[[Rosai-Dorfman disease]] - histiocyte nuclei large (~2-3x lymphocyte) and round with a prominent nucleoli. | |||
*[[Dermatopathic lymphadenopathy]] - histiocytes have (melanin) pigment. | |||
===Images=== | |||
<gallery> | |||
Image: Sinus histiocytosis -- intermed mag.jpg | SH - intermed. mag. | |||
Image: Sinus histiocytosis -- high mag.jpg | SH - high mag. | |||
Image: Sinus histiocytosis - deep -- high mag.jpg | SH - high mag. | |||
</gallery> | |||
==Sign out== | |||
*The finding is often ignored; may be signed out as ''morphologically benign lymph nodes''. | |||
==See also== | ==See also== | ||