Difference between revisions of "Xanthogranulomatous cholecystitis"
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| Micro = cholesterol clefts, [[granulomas]] | |||
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| Site = [[gallbladder]] | |||
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| ClinDDx = [[gallbladder carcinoma]], [[acute cholecystitis]] | |||
}} | |||
'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''', is an uncommon pathology of the [[gallbladder]]. | '''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''', is an uncommon pathology of the [[gallbladder]]. | ||
==General== | ==General== | ||
*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal | last1 = Hale | first1 = MD. | last2 = Roberts | first2 = KJ. | last3 = Hodson | first3 = J. | last4 = Scott | first4 = N. | last5 = Sheridan | first5 = M. | last6 = Toogood | first6 = GJ. | title = Xanthogranulomatous cholecystitis: a European and global perspective. | journal = HPB (Oxford) | volume = | issue = | pages = | month = Aug | year = 2013 | doi = 10.1111/hpb.12152 | PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal | last1 = Alvi | first1 = AR. | last2 = Jalbani | first2 = I. | last3 = Murtaza | first3 = G. | last4 = Hameed | first4 = A. | title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. | journal = J Minim Access Surg | volume = 9 | issue = 3 | pages = 109-15 | month = Jul | year = 2013 | doi = 10.4103/0972-9941.115368 | PMID = 24019688 }}</ref> | *Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal | last1 = Hale | first1 = MD. | last2 = Roberts | first2 = KJ. | last3 = Hodson | first3 = J. | last4 = Scott | first4 = N. | last5 = Sheridan | first5 = M. | last6 = Toogood | first6 = GJ. | title = Xanthogranulomatous cholecystitis: a European and global perspective. | journal = HPB (Oxford) | volume = | issue = | pages = | month = Aug | year = 2013 | doi = 10.1111/hpb.12152 | PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal | last1 = Alvi | first1 = AR. | last2 = Jalbani | first2 = I. | last3 = Murtaza | first3 = G. | last4 = Hameed | first4 = A. | title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. | journal = J Minim Access Surg | volume = 9 | issue = 3 | pages = 109-15 | month = Jul | year = 2013 | doi = 10.4103/0972-9941.115368 | PMID = 24019688 }}</ref> | ||
**Approximately 2% in one series of gallbladders.<ref name=pmid3584484>{{Cite journal | last1 = Roberts | first1 = KM. | last2 = Parsons | first2 = MA. | title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. | journal = J Clin Pathol | volume = 40 | issue = 4 | pages = 412-7 | month = Apr | year = 1987 | doi = | PMID = 3584484 }}</ref> | |||
*May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal | last1 = Martins | first1 = PN. | last2 = Sheiner | first2 = P. | last3 = Facciuto | first3 = M. | title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. | journal = Hepatobiliary Pancreat Dis Int | volume = 11 | issue = 5 | pages = 549-52 | month = Oct | year = 2012 | doi = | PMID = 23060404 }}</ref> | *May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal | last1 = Martins | first1 = PN. | last2 = Sheiner | first2 = P. | last3 = Facciuto | first3 = M. | title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. | journal = Hepatobiliary Pancreat Dis Int | volume = 11 | issue = 5 | pages = 549-52 | month = Oct | year = 2012 | doi = | PMID = 23060404 }}</ref> | ||
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*[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal | last1 = Cecava | first1 = ND. | last2 = Andrews | first2 = R. | title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. | journal = J Radiol Case Rep | volume = 5 | issue = 4 | pages = 19-24 | month = | year = 2011 | doi = 10.3941/jrcr.v5i4.696 | PMID = 22470787 }}</ref> | *[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal | last1 = Cecava | first1 = ND. | last2 = Andrews | first2 = R. | title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. | journal = J Radiol Case Rep | volume = 5 | issue = 4 | pages = 19-24 | month = | year = 2011 | doi = 10.3941/jrcr.v5i4.696 | PMID = 22470787 }}</ref> | ||
==Sign out== | |||
<pre> | |||
GALLBLADDER, CHOLECYSTECTOMY: | |||
- XANTHOGRANULOMATOUS CHOLECYSTITIS. | |||
- CHOLELITHIASIS. | |||
</pre> | |||
===Micro=== | |||
The sections show gallbladder wall with cholesterol clefts, multinucleated giant cells and | |||
mononuclear cells. No metaplasia, nuclear atypia or dysplasia is apparent. | |||
==See also== | ==See also== | ||