Difference between revisions of "Prostate cancer"

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(→‎General: tweak)
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===Management===
===Management===
====Dirty first approximation====
====Dirty first approximation====
The management changes between Gleason 6, 7 & 8; typically, the implications are:
*The management changes between Gleason score 6, 7 and 8.
* Gleason 6: watchful waiting ''or'' radioactive seeds; surgery if patient wants.
 
* Gleason 7: do something - surgery ''or'' radiation therapy.
Typically, the implications are:
* Gleason 8+: bad cancer - do something quickly!
* Gleason 6: observation ''or'' radioactive seeds; surgery if patient wants.
* Gleason 7: do something -- surgery ''or'' radiation therapy.
* Gleason 8+: bad cancer -- do something quickly!


Bottom line:  
Bottom line:  
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=====Active surveillance=====
=====Active surveillance=====
One set of criteria (''Klotz''<ref name=pmid22314081/><ref>{{Cite journal  | last1 = Klotz | first1 = L. | title = Active surveillance for prostate cancer: for whom? | journal = J Clin Oncol | volume = 23 | issue = 32 | pages = 8165-9 | month = Nov | year = 2005 | doi = 10.1200/JCO.2005.03.3134 | PMID = 16278468 }}</ref>):
The ''Klotz'' criteria for active surveillance:<ref name=pmid22314081/><ref>{{Cite journal  | last1 = Klotz | first1 = L. | title = Active surveillance for prostate cancer: for whom? | journal = J Clin Oncol | volume = 23 | issue = 32 | pages = 8165-9 | month = Nov | year = 2005 | doi = 10.1200/JCO.2005.03.3134 | PMID = 16278468 }}</ref>
*Gleason score 6 or less.
*Gleason score 6 or less.
*All biopsies cores < 50% involvement.
*All biopsies cores < 50% involvement.
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