Difference between revisions of "Placenta"
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(→Maternal floor infarction: +abbrev.) |
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==Maternal floor infarction== | ==Maternal floor infarction== | ||
*Abbreviated ''MFI''. | |||
*Formally ''placental maternal floor infarction''. | *Formally ''placental maternal floor infarction''. | ||
*[[AKA]] ''massive perivillous fibrin deposition''.<ref name=Ref_Placenta367>{{Ref Placenta|367}}</ref> | *[[AKA]] ''massive perivillous fibrin deposition''.<ref name=Ref_Placenta367>{{Ref Placenta|367}}</ref> | ||
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*'''''Not''''' a true infact. | *'''''Not''''' a true infact. | ||
**It is really fibrin deposition.<ref name=Ref_TPoSP178>{{Ref TPoSP|178}}</ref> | **It is really fibrin deposition.<ref name=Ref_TPoSP178>{{Ref TPoSP|178}}</ref> | ||
* | |||
* | Associations: | ||
*[[Intrauterine growth restriction]] (IUGR).<ref name=pmid18641412>{{Cite journal | last1 = Roberts | first1 = DJ. | last2 = Post | first2 = MD. | title = The placenta in pre-eclampsia and intrauterine growth restriction. | journal = J Clin Pathol | volume = 61 | issue = 12 | pages = 1254-60 | month = Dec | year = 2008 | doi = 10.1136/jcp.2008.055236 | PMID = 18641412 }}</ref> | |||
*Anti-phospholipid antibody (APLA) syndrome.<ref name=pmid12066949>{{cite journal |author=Sebire NJ, Backos M, Goldin RD, Regan L |title=Placental massive perivillous fibrin deposition associated with antiphospholipid antibody syndrome |journal=BJOG |volume=109 |issue=5 |pages=570–3 |year=2002 |month=May |pmid=12066949 |doi= |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1470-0328&date=2002&volume=109&issue=5&spage=570}}</ref> | |||
**APLA is associated with recurrent miscarriage - can be treated with heparin + ASA.<ref name=pmid12066949/> | **APLA is associated with recurrent miscarriage - can be treated with heparin + ASA.<ref name=pmid12066949/> | ||
*Pregnancy-induced [[hypertension]].<ref name=pmid8569189>{{Cite journal | last1 = Kanfer | first1 = A. | last2 = Bruch | first2 = JF. | last3 = Nguyen | first3 = G. | last4 = He | first4 = CJ. | last5 = Delarue | first5 = F. | last6 = Flahault | first6 = A. | last7 = Nessmann | first7 = C. | last8 = Uzan | first8 = S. | title = Increased placental antifibrinolytic potential and fibrin deposits in pregnancy-induced hypertension and preeclampsia. | journal = Lab Invest | volume = 74 | issue = 1 | pages = 253-8 | month = Jan | year = 1996 | doi = | PMID = 8569189 }}</ref> | |||
===Gross=== | ===Gross=== | ||
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- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. | - THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS. | ||
- FETAL MEMBRANES WITHIN NORMAL LIMITS. | - FETAL MEMBRANES WITHIN NORMAL LIMITS. | ||
- SMALL PLACENTAL DISC WITH MASSIVE PERIVILLOUS FIBRIN DEPOSITION. | - SMALL PLACENTAL DISC WITH MASSIVE PERIVILLOUS FIBRIN DEPOSITION, SEE COMMENT. | ||
COMMENT: | |||
Massive perivillous fibrin deposition (MPVFD) is associated with intrauterine | |||
growth restriction (IUGR). MPVFD is described in association with in | |||
anti-phospholipid antibody (APLA) syndrome, pregnancy-induced hypertension and | |||
congenital infections. Perivillous fibrin deposition may be seen in diabetes. | |||
There is no apparent infection. Changes suggestive of decidual vasculopathy | |||
are not apparent. Changes suggestive of fetal thrombotic vasculopathy are | |||
not identified. | |||
</pre> | </pre> | ||