Difference between revisions of "Endometrium"

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===Microscopic===
===Microscopic===
Features:
Features:<ref name=pmid16873562/>
*Glands:  
*Glands:  
**Straight, tubular, composed of tall pseudostratified columnar cells - '''key feature'''.
**Straight, tubular, composed of tall pseudostratified columnar cells - '''key feature'''.
**Mitotic figures - '''key feature'''.
**Mitotic figures - '''key feature'''. †
**NO vacuolation.
**NO mucus secretion.
*Stroma:  
*Stroma:  
**Cellular stroma (spindle cells).
**Cellular stroma (spindle cells).
**Mitoses.
**Mitoses.
***Usually harder to find than in the glands.
***Usually harder to find than in the glands.
Notes:
* † McCluggage says one shouldn't call ''PPE'' without mitoses, as some pseudostratification can be seen in [[atrophic endometrium]].<ref name=pmid16873562>{{Cite journal  | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 }}</ref>
** There is no guidance on how hard one should look. VL suggests searching ~ 10 mm^2 with the 20x objective. This represents approximately ~ 10 fields of view with a microscope that has a 22 mm eye piece.
* Significant negatives:
** No vacuolation.
** No mucus secretion.


DDx:
DDx:
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