Difference between revisions of "Prostate gland"

Jump to navigation Jump to search
Line 519: Line 519:
*Mitoses are not a common feature - don't waste time looking for them.
*Mitoses are not a common feature - don't waste time looking for them.


===Mimics===
====Mimics====
Mimics of prostate adenocarcinoma:<ref>{{Ref TPoSP|100-3}}</ref>
Mimics of prostate adenocarcinoma:<ref>{{Ref TPoSP|100-3}}</ref>
{| class="wikitable sortable"
{| class="wikitable sortable"
Line 584: Line 584:
Memory device: '''AAABBRS''' = atrophy, adenosis, adenosis (sclerosing), basal cell hyperplasia, bulbourethral gland, radiation, seminal vesicles.
Memory device: '''AAABBRS''' = atrophy, adenosis, adenosis (sclerosing), basal cell hyperplasia, bulbourethral gland, radiation, seminal vesicles.


===Grading===
===Gleason grading system===
There is only one grading system that any one talks about - the Gleason system.
Overview:
 
*This system is only one any one talks about.
====Gleason grading system====
*Score range: 6-10.
*Score range: 2-10.
**Technically 2-10... but almost no one uses 2-5.
*Reported as on biopsy as: (primary pattern) + (secondary pattern ''or'' tertiary pattern with the highest grade) = sum.
*Reported as on biopsy as: (primary pattern) + (secondary pattern ''or'' tertiary pattern with the highest grade) = sum.
**e.g. ''Gleason score 3+4=7'' means: pattern 3 is present and dominant, pattern 4 is the remainder of the tumour - but present in a lesser amount than pattern 3.
**e.g. ''Gleason score 3+4=7'' means: pattern 3 is present and dominant, pattern 4 is the remainder of the tumour - but present in a lesser amount than pattern 3.
Line 597: Line 597:


Examples:
Examples:
*A biopsy has 80% pattern 4, 15.1% pattern 3 and 4.9% pattern 5... it would be reported as: 4+5=9.
*A biopsy has 80% pattern 4, 16% pattern 3 and 4% pattern 5... it would be reported as: 4+5=9.
*A prostatectomy has 80% pattern 4, 15.1% pattern 3 and 4.9% pattern 5... it would be reported as: 4+3=7 with tertiary pattern 5.
*A prostatectomy has 80% pattern 4, 16% pattern 3 and 4% pattern 5... it would be reported as: 4+3=7 with tertiary pattern 5.


Testing yourself:
Testing yourself: