Difference between revisions of "Prostate gland"
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m (→Epstein & Hutchins classification: more) |
(→Chronic inflammation: split) |
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*[http://commons.wikimedia.org/wiki/File:Acute_inflammation_of_prostate.jpg Prostate with acute inflammation (WC)]. | *[http://commons.wikimedia.org/wiki/File:Acute_inflammation_of_prostate.jpg Prostate with acute inflammation (WC)]. | ||
==Chronic inflammation not otherwise specified== | |||
===General=== | |||
=== | *Common. | ||
*Non-specific. | *Non-specific finding. | ||
*Etiology | *Etiology usually not apparent on histomorphology. | ||
===Microscopic=== | |||
Features: | Features: | ||
*Lymphocytes within the glands, between the epithelial cells ''or'' within the stroma - '''key feature'''. | *Lymphocytes within the glands, between the epithelial cells ''or'' within the stroma - '''key feature'''. | ||
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*[http://commons.wikimedia.org/wiki/File:Inflammation_of_prostate.jpg Prostate with chronic inflammation (WC)]. | *[http://commons.wikimedia.org/wiki/File:Inflammation_of_prostate.jpg Prostate with chronic inflammation (WC)]. | ||
==Granulomatous prostatitis== | |||
*[[AKA]] ''prostate granuloma''. | |||
===General=== | |||
*Common. | *Common. | ||
*Usually secondary to BCG treatment of [[urinary bladder cancer|bladder cancer]]. | *Usually secondary to BCG treatment of [[urinary bladder cancer|bladder cancer]]. | ||
*Several classifications exist<ref name=pmid17092284>{{Cite journal | last1 = Uzoh | first1 = CC. | last2 = Uff | first2 = JS. | last3 = Okeke | first3 = AA. | title = Granulomatous prostatitis. | journal = BJU Int | volume = 99 | issue = 3 | pages = 510-2 | month = Mar | year = 2007 | doi = 10.1111/j.1464-410X.2006.06585.x | PMID = 17092284 | URL = http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2006.06585.x/full }}</ref> - the most commonly used is by ''Epstein & Hutchins''. | *Several classifications exist<ref name=pmid17092284>{{Cite journal | last1 = Uzoh | first1 = CC. | last2 = Uff | first2 = JS. | last3 = Okeke | first3 = AA. | title = Granulomatous prostatitis. | journal = BJU Int | volume = 99 | issue = 3 | pages = 510-2 | month = Mar | year = 2007 | doi = 10.1111/j.1464-410X.2006.06585.x | PMID = 17092284 | URL = http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2006.06585.x/full }}</ref> - the most commonly used is by ''Epstein & Hutchins''. | ||
====Epstein & Hutchins classification==== | |||
The groupings:<ref name=pmid6432674>{{Cite journal | last1 = Epstein | first1 = JI. | last2 = Hutchins | first2 = GM. | title = Granulomatous prostatitis: distinction among allergic, nonspecific, and post-transurethral resection lesions. | journal = Hum Pathol | volume = 15 | issue = 9 | pages = 818-25 | month = Sep | year = 1984 | doi = | PMID = 6432674 }}</ref> | The groupings:<ref name=pmid6432674>{{Cite journal | last1 = Epstein | first1 = JI. | last2 = Hutchins | first2 = GM. | title = Granulomatous prostatitis: distinction among allergic, nonspecific, and post-transurethral resection lesions. | journal = Hum Pathol | volume = 15 | issue = 9 | pages = 818-25 | month = Sep | year = 1984 | doi = | PMID = 6432674 }}</ref> | ||
#Non-specific. | #Non-specific. | ||
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#*#[[Churg-Strauss syndrome]]. | #*#[[Churg-Strauss syndrome]]. | ||
===Microscopic=== | |||
Features: | Features: | ||
*[[Granulomas]] in | *[[Granulomas]] in the prostate - '''key feature'''. | ||
**Palisading granulomas with a necrotic core (similar to a [[rheumatoid nodule]]) consistent a prior TURP.<ref name=pmid6703198/> | |||
*+/-Eosinophils. | |||
Images: | Images: | ||
*[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck.jpg Granulomatous inflammation of the prostate/bladder neck - low mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck.jpg Granulomatous inflammation of the prostate/bladder neck - low mag. (WC)]. | ||
*[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck_high_mag.jpg Granulomatous inflammation of the prostate/bladder neck - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Granulomatous_inflammation_of_bladder_neck_high_mag.jpg Granulomatous inflammation of the prostate/bladder neck - high mag. (WC)]. | ||
===Stains=== | |||
*[[GMS stain]]. | |||
*[[Ziehl-Neelsen stain]]. | |||
Note: | |||
*Stains are indicated when there is a suspicion of an infective etiology based on histomorphology or clinical information (e.g. immunosuppression). | |||
==Atrophy of the prostate== | ==Atrophy of the prostate== | ||