Difference between revisions of "Liver neoplasms"
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*[http://commons.wikimedia.org/wiki/File:Hepatic_adenoma_low_mag_reticulin.jpg Hepatic adenoma - reticulin (WC)]. | *[http://commons.wikimedia.org/wiki/File:Hepatic_adenoma_low_mag_reticulin.jpg Hepatic adenoma - reticulin (WC)]. | ||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675(06)71565-0&figureId=fig2 Hepatic adenoma (pathconsultddx.com)]. | *[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675(06)71565-0&figureId=fig2 Hepatic adenoma (pathconsultddx.com)]. | ||
*[http://www.ajronline.org/cgi/content-nw/full/182/6/1520/FIG3 | *[http://www.ajronline.org/cgi/content-nw/full/182/6/1520/FIG3 Hepatic adenoma (ajronline.org)]. | ||
*[http://radiographics.rsna.org/content/22/5/1023.figures-only Series of liver micrographs including hepatic adenoma (radiographics.rsna.org)]. | *[http://radiographics.rsna.org/content/22/5/1023.figures-only Series of liver micrographs including hepatic adenoma (radiographics.rsna.org)]. | ||
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Varied architecture - may be:<ref>GLP P.590-1.</ref> | Varied architecture - may be:<ref>GLP P.590-1.</ref> | ||
*Pseudoglandular - can be confused with adenocarcinoma | *Pseudoglandular - can be confused with adenocarcinoma. | ||
*Trabecular | *Trabecular. | ||
*Fibrolamellar | *Fibrolamellar. | ||
*Solid. | *Solid. | ||
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ASIDE: | ASIDE: | ||
*''Trabecula'' = ''little beam''. | *''Trabecula'' = ''little beam''. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Hepatocellular_carcinoma_low_mag.jpg HCC - low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Hepatocellular_carcinoma_intermed_mag.jpg HCC - intermed mag. (WC)]. | |||
====Fibrolamellar HCC==== | ====Fibrolamellar HCC==== | ||
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*HepPar-1 +ve; may be neg. in high grade tumours. | *HepPar-1 +ve; may be neg. in high grade tumours. | ||
*AFP +ve; may be neg. even if the serum AFP is elevated. | *AFP +ve; may be neg. even if the serum AFP is elevated. | ||
*CK18 +ve<ref>AP 28 May 2009.</ref> | *CK18 +ve.<ref>AP. 28 May 2009.</ref> | ||
==Cholangiocarcioma== | ==Cholangiocarcioma== | ||
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===Microscopic=== | ===Microscopic=== | ||
*Histologic features are dependent on primary and degree of differentiation. | *Histologic features are dependent on primary and degree of differentiation. | ||
Image: [http://commons.wikimedia.org/wiki/File:Adenocarcinoma_liver_metastasis.jpg Liver metastasis - adenocarcinoma (WC)]. | |||
===IHC=== | ===IHC=== | ||