Difference between revisions of "Germ cell tumours"

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==Yolk sac tumour==

*Abbreviated ''YST''.

*[[AKA]] ''endodermal sinus tumour''.

===General===

*~~Tumour also known as ''endodermal sinus tumour''~~.

*Rare.

*Aggressive - especially extragonadal tumours.<ref name=pmid18767035>

~~====~~Epidemiology~~====~~

Epidemiology:

*Most common GCT in infants and young boys.

*Bimodal age distribution:<ref name=pmid18767035>{{Cite journal | last1 = Shah | first1 = JP. | last2 = Kumar | first2 = S. | last3 = Bryant | first3 = CS. | last4 = Ali-Fehmi | first4 = R. | last5 = Malone | first5 = JM. | last6 = Deppe | first6 = G. | last7 = Morris | first7 = RT. | title = A population-based analysis of 788 cases of yolk sac tumors: A comparison of males and females. | journal = Int J Cancer | volume = 123 | issue = 11 | pages = 2671-5 | month = Dec | year = 2008 | doi = 10.1002/ijc.23792 | PMID = 18767035 }}</ref>

**<4 years.

**10-30 years.

Clinical:

*Elevated AFP.

===Gross===

*White/yellow mucinous infiltrative mass.<ref name=Ref_PCPBoD8_510>{{Ref PCPBoD8|510}}</ref>

===Microscopic===

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*[http://www.webpathology.com/image.asp?n=6&Case=34 Hyaline globules (webpathology.com)].

*[http://path.upmc.edu/cases/case152.html Yolk sac tumour - case 1 - several images (upmc.edu)].

*[http://path.upmc.edu/cases/case492.html Yolk ~~sca~~ tumour - case 2 - several images (upmc.edu)].

*[http://path.upmc.edu/cases/case492.html Yolk sac tumour - case 2 - several images (upmc.edu)].

*[http://www.moffitt.org/CCJRoot/v11n6/pdf/374.pdf Yolk sac tumour (moffitt.org)].<ref name=pmid15625525>{{Cite journal | last1 = Sesterhenn | first1 = IA. | last2 = Davis | first2 = CJ. | title = Pathology of germ cell tumors of the testis. | journal = Cancer Control | volume = 11 | issue = 6 | pages = 374-87 | month = | year = | doi = | PMID = 15625525 }}</ref>

===IHC===

Difference between revisions of "Germ cell tumours"

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@@ Line 118: / Line 118: @@
 ==Yolk sac tumour==
+*Abbreviated ''YST''.
+*[[AKA]] ''endodermal sinus tumour''.
 ===General===
-*Tumour also known as ''endodermal sinus tumour''.
+*Rare.
+*Aggressive - especially extragonadal tumours.<ref name=pmid18767035>
-====Epidemiology====
+Epidemiology:
 *Most common GCT in infants and young boys.
+*Bimodal age distribution:<ref name=pmid18767035>{{Cite journal  | last1 = Shah | first1 = JP. | last2 = Kumar | first2 = S. | last3 = Bryant | first3 = CS. | last4 = Ali-Fehmi | first4 = R. | last5 = Malone | first5 = JM. | last6 = Deppe | first6 = G. | last7 = Morris | first7 = RT. | title = A population-based analysis of 788 cases of yolk sac tumors: A comparison of males and females. | journal = Int J Cancer | volume = 123 | issue = 11 | pages = 2671-5 | month = Dec | year = 2008 | doi = 10.1002/ijc.23792 | PMID = 18767035 }}</ref>
+**<4 years.
+**10-30 years.
+Clinical:
+*Elevated AFP.
+===Gross===
+*White/yellow mucinous infiltrative mass.<ref name=Ref_PCPBoD8_510>{{Ref PCPBoD8|510}}</ref>
 ===Microscopic===
@@ Line 159: / Line 171: @@
 *[http://www.webpathology.com/image.asp?n=6&Case=34 Hyaline globules (webpathology.com)].
 *[http://path.upmc.edu/cases/case152.html Yolk sac tumour - case 1 - several images (upmc.edu)].
-*[http://path.upmc.edu/cases/case492.html Yolk sca tumour - case 2 - several images (upmc.edu)].
+*[http://path.upmc.edu/cases/case492.html Yolk sac tumour - case 2 - several images (upmc.edu)].
+*[http://www.moffitt.org/CCJRoot/v11n6/pdf/374.pdf Yolk sac tumour (moffitt.org)].<ref name=pmid15625525>{{Cite journal  | last1 = Sesterhenn | first1 = IA. | last2 = Davis | first2 = CJ. | title = Pathology of germ cell tumors of the testis. | journal = Cancer Control | volume = 11 | issue = 6 | pages = 374-87 | month =  | year =  | doi =  | PMID = 15625525 }}</ref>
 ===IHC===