Difference between revisions of "Gynecologic cytopathology"
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| Line 576: | Line 576: | ||
DDx: | DDx: | ||
*[[AGC]] - no prominent nucleoli, not 3-dimensional. | *[[AGC]] - no prominent nucleoli, not 3-dimensional. | ||
*[[Endometrial adenocarcinoma in situ]]. | |||
Image: | Image: | ||
*[http://commons.wikimedia.org/wiki/File:Cervical_AIS,_ThinPrep.jpg AIS endocervix (wikimedia.org)]. | *[http://commons.wikimedia.org/wiki/File:Cervical_AIS,_ThinPrep.jpg AIS endocervix (wikimedia.org)]. | ||
==Endometrial adenocarcinoma in situ== | |||
*[[AKA]] ''adenocarcinoma in situ of the endometrium''. | |||
===General=== | |||
*Management - like AGC and other types of AIS: coloscopy + endometrial biopsy. | |||
===Cytopathology=== | |||
Features: | |||
*Single cells or cluster of small cells with: | |||
**Moderate nuclear enlargement ~2x intermediate cell nucleus. | |||
**Nuclear hyperchromasia. | |||
**Coarse chromatin. | |||
**Nucleoli - prominent - '''key feature'''. | |||
**+/-Mitoses. | |||
**+/-Intracytoplasmic neutrophils. | |||
*Apoptotic/necrotic cells. | |||
DDx: | |||
*[[AGC]] - no prominent nucleoli, not 3-dimensional. | |||
*[[Endocervical adenocarcinoma in situ]]. | |||
=Waffle categories= | =Waffle categories= | ||