Difference between revisions of "Trophoblast"

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| '''Syncytiotrophoblast'''
| '''Syncytiotrophoblast'''
| '''Villous intermediate<br>trophoblast'''
| '''Villous intermediate<br>trophoblast'''
| '''Implanation site<br>intermediate trophoblast'''
| '''Implantation site<br>intermediate trophoblast'''
| '''Chorionic-type<br>intermediate trophoblast'''
| '''Chorionic-type<br>intermediate trophoblast'''
|-
|-
Line 30: Line 30:
| Cytoplasm
| Cytoplasm
| minimal, clear to granular
| minimal, clear to granular
| abundant, vacuolated
| abundant, vacuolated, basophilic (???)
| abundant & eosinophilic to clear
| abundant & eosinophilic to clear
| abundant & eosinophilic
| abundant & eosinophilic
Line 50: Line 50:
|-
|-
| IHC
| IHC
| beta-hCG ???
| beta-hCG -ve (???), p63 +ve<ref name=pmid19188816>{{Cite journal  | last1 = Zhang | first1 = HJ. | last2 = Xue | first2 = WC. | last3 = Siu | first3 = MK. | last4 = Liao | first4 = XY. | last5 = Ngan | first5 = HY. | last6 = Cheung | first6 = AN. | title = P63 expression in gestational trophoblastic disease: correlation with proliferation and apoptotic dynamics. | journal = Int J Gynecol Pathol | volume = 28 | issue = 2 | pages = 172-8 | month = Mar | year = 2009 | doi = 10.1097/PGP.0b013e318189555b | PMID = 19188816 }}</ref>
| beta-hCG
| beta-hCG +ve
| ???
| p63 +ve,<ref name=pmid19188816/> PLAP +ve
| inhibin+, hPL+, beta-hCG-<ref name=pmid1694585>{{cite journal |author=Yeh IT, O'Connor DM, Kurman RJ |title=Intermediate trophoblast: further immunocytochemical characterization |journal=Mod. Pathol. |volume=3 |issue=3 |pages=282–7 |year=1990 |month=May |pmid=1694585 |doi= |url=}}</ref> CD146+,<ref name=pmid10451481>{{Cite journal  | last1 = Shih | first1 = IM. | title = The role of CD146 (Mel-CAM) in biology and pathology. | journal = J Pathol | volume = 189 | issue = 1 | pages = 4-11 | month = Sep | year = 1999 | doi = 10.1002/(SICI)1096-9896(199909)189:14::AID-PATH3323.0.CO;2-P | PMID = 10451481 }}</ref> p63-
| inhibin +ve, hPL +ve, beta-hCG -ve<ref name=pmid1694585>{{cite journal |author=Yeh IT, O'Connor DM, Kurman RJ |title=Intermediate trophoblast: further immunocytochemical characterization |journal=Mod. Pathol. |volume=3 |issue=3 |pages=282–7 |year=1990 |month=May |pmid=1694585 |doi= |url=}}</ref> CD146+,<ref name=pmid10451481>{{Cite journal  | last1 = Shih | first1 = IM. | title = The role of CD146 (Mel-CAM) in biology and pathology. | journal = J Pathol | volume = 189 | issue = 1 | pages = 4-11 | month = Sep | year = 1999 | doi = 10.1002/(SICI)1096-9896(199909)189:14::AID-PATH3323.0.CO;2-P | PMID = 10451481 }}</ref> p63 -ve
| hPL+/-, p63+, CD146-  
| hPL +ve/-ve, p63 +ve, CD146 -ve
|-
|-
| Image
| Image