Difference between revisions of "Salivary glands"
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(→Mucocele: redirect) |
(→Sebaceous carcinoma: +basal cell adenocarcinoma) |
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| Line 891: | Line 891: | ||
*CAM5.2 +ve -- epithelial component. | *CAM5.2 +ve -- epithelial component. | ||
*p63 +ve -- myoepithelial component. | *p63 +ve -- myoepithelial component. | ||
==Basal cell adenocarcinoma== | |||
===General=== | |||
*Malignant. | |||
===Microscopic=== | |||
Features: | |||
#Lesion is '''not''' encapsulated - '''key feature'''. | |||
#Basal-like cells: | |||
#*Basophilic cells - '''key feature'''. | |||
#*Usually in nests. | |||
#**May be bilayered tubules ''or'' [[trabeculae]]. | |||
#*Large basophilic nucleus. | |||
#*Minimal-to-moderate eosinophilic cytoplasm. | |||
#Stromal cells. | |||
#*Plump spindle cells without significant nuclear atypia. | |||
#**Stromal cell nuclei width ~= diameter [[RBC]]. | |||
#*Dense hyaline stroma. | |||
#Tubular component. | |||
#*Within basal component, may be minimal. | |||
DDx: | |||
*[[Adenoid cystic carcinoma]]. | |||
*[[Basal cell adenoma]]. | |||
==Sebaceous carcinoma== | ==Sebaceous carcinoma== | ||