Difference between revisions of "Stomach"

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==Helicobacter gastritis==

===General===

*Several Helicobacter species can cause gastritis~~; H.~~ pylori most common

*Several Helicobacter species can cause gastritis:

**''Helicobacter pylori'' - most common.

**''Helicobacter heilmannii''.

===~~Finding Helicobacter~~===

Epidemiologic associations:

Helicobacter infections are associated with:<ref>{{Ref PBoD|814}}</ref>

*Gastritis.

*Peptic ulcers.

*Cancer.

**Carcinoma.

**[[MALT lymphoma]].

===Microscopic===

Features:

*Small - smaller than the nucleus of the gastric foveolar cell.

**On 400x they are still possible to miss.

*Commonly have a "v" shape.

*Look close to the opening of the gastric glands.

*Are often are found in groups.

*Location - can be antrum and/or body.<ref>{{cite journal |author=Maaroos HI, Kekki M, Villako K, Sipponen P, Tamm A, Sadeniemi L |title=The occurrence and extent of Helicobacter pylori colonization and antral and body gastritis profiles in an Estonian population sample |journal=Scand. J. Gastroenterol. |volume=25 |issue=10 |pages=1010-7 |year=1990 |month=October |pmid=2263873 |doi= |url=}}</ref>

*Helicobacter don't like the intestinal mucosa or mucosa that has undergone intestinal metaplasia -- you're unlikely to find 'em there.

*''Helicobacter pylori'':

**Typically have a "v" shape ''or'' a comma-like shape.

*''Helicobacter heilmannii'':

**Corkscrew appearance.

Images:

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*[http://commons.wikimedia.org/wiki/Category:Helicobacter_gastritis Set of images - HP gastritis (WC)].

===~~Epidemiologic associations~~===

===Stains===

~~Helicobacter infections are associated with:<ref>{{Ref PBoD|814}}</ref>~~

*[[Cresyl violet stain]] - background and organisms blue.

*~~Gastritis~~.

*[[Warthin-Starry stain]] - background yellow, organisms black.

*~~Peptic ulcers~~.

*Cancer.

===IHC===

**Carcinoma.

*Helicobacter pylori IHC stain +ve.

**[[MALT lymphoma]].

==Intestinal metaplasia==

Difference between revisions of "Stomach"

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@@ Line 228: / Line 228: @@
 ==Helicobacter gastritis==
 ===General===
-*Several Helicobacter species can cause gastritis; H. pylori most common
+*Several Helicobacter species can cause gastritis:
+**''Helicobacter pylori'' - most common.
+**''Helicobacter heilmannii''.
-===Finding Helicobacter===
+Epidemiologic associations:
+Helicobacter infections are associated with:<ref>{{Ref PBoD|814}}</ref>
+*Gastritis.
+*Peptic ulcers.
+*Cancer.
+**Carcinoma.
+**[[MALT lymphoma]].
+===Microscopic===
+Features:
 *Small - smaller than the nucleus of the gastric foveolar cell.
 **On 400x they are still possible to miss.
-*Commonly have a "v" shape.
 *Look close to the opening of the gastric glands.
 *Are often are found in groups.
 *Location - can be antrum and/or body.<ref>{{cite journal |author=Maaroos HI, Kekki M, Villako K, Sipponen P, Tamm A, Sadeniemi L |title=The occurrence and extent of Helicobacter pylori colonization and antral and body gastritis profiles in an Estonian population sample |journal=Scand. J. Gastroenterol. |volume=25 |issue=10 |pages=1010-7 |year=1990 |month=October |pmid=2263873 |doi= |url=}}</ref>
 *Helicobacter don't like the intestinal mucosa or mucosa that has undergone intestinal metaplasia -- you're unlikely to find 'em there.
+*''Helicobacter pylori'':
+**Typically have a "v" shape ''or'' a comma-like shape.
+*''Helicobacter heilmannii'':
+**Corkscrew appearance.
 Images:
@@ Line 246: / Line 260: @@
 *[http://commons.wikimedia.org/wiki/Category:Helicobacter_gastritis Set of images - HP gastritis (WC)].
-===Epidemiologic associations===
+===Stains===
-Helicobacter infections are associated with:<ref>{{Ref PBoD|814}}</ref>
+*[[Cresyl violet stain]] - background and organisms blue.
-*Gastritis.
+*[[Warthin-Starry stain]] - background yellow, organisms black.
-*Peptic ulcers.
-*Cancer.
+===IHC===
-**Carcinoma.
+*Helicobacter pylori IHC stain +ve.
-**[[MALT lymphoma]].
 ==Intestinal metaplasia==