Difference between revisions of "Melanocytic lesions"
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(tweak subtypes) |
(→Neurocristic hamartoma: +Clark nevus) |
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*Intraepidermal ascent of cells is usually suggestive of melanoma. | *Intraepidermal ascent of cells is usually suggestive of melanoma. | ||
**In acral sites the criteria are relaxed, i.e. this is considered benign for this site. | **In acral sites the criteria are relaxed, i.e. this is considered benign for this site. | ||
==Clark nevus== | |||
*[[AKA]] ''dyplastic nevus''. | |||
===General=== | |||
*Usually benign. | |||
*Generally ''not'' a precursor of ''[[melanoma]]'', as the name ''dysplastic nevus'' may suggest. | |||
**Large numbers of these nevi (10-100) are seen in ''dysplastic nevus syndrome''.<ref>{{OMIM|155600}}</ref> | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP502>{{Ref WMSP|502}}</ref> | |||
*Melanocytes "bridges" between sides of rete ridges. | |||
*Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis. | |||
*Usually moderate nuclear atypia (nucleoli present). | |||
==Neurocristic hamartoma== | ==Neurocristic hamartoma== | ||