Difference between revisions of "Malignant melanoma"
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(→Microscopic: tweak) |
m (→Skin: +regression) |
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*Cells get smaller. | *Cells get smaller. | ||
*Mitoses decrease. | *Mitoses decrease. | ||
*Pigmentation decrease. | *Pigmentation decrease. | ||
====Regression of melanoma==== | |||
=====General===== | |||
*Complete regression without metastases estimated to be 10-20%.<ref name=pmid11459861/> | |||
*Common ~25% of cases.<ref name=pmid11459861>{{Cite journal | last1 = Printz | first1 = C. | title = Spontaneous regression of melanoma may offer insight into cancer immunology. | journal = J Natl Cancer Inst | volume = 93 | issue = 14 | pages = 1047-8 | month = Jul | year = 2001 | doi = | PMID = 11459861 | URL = http://jnci.oxfordjournals.org/content/93/14/1047.full }}</ref> | |||
**Poor prognostic feature. | |||
=====Microscopic===== | |||
Features - all required: | |||
*No melanocytes. | |||
*Melanophages. | |||
*Fibrosis. | |||
*Thinned epidermis. | |||
*Telangiectatic vessels. | |||
*Lymphocytes. | |||
===Metastatic versus primary=== | ===Metastatic versus primary=== | ||