Difference between revisions of "Henoch–Schönlein purpura"

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#[[IgA nephropathy]].
#[[IgA nephropathy]].
#[[Leukocytoclastic vasculitis]].<ref name=pmid9713395>{{Cite journal  | last1 = Kraft | first1 = DM. | last2 = Mckee | first2 = D. | last3 = Scott | first3 = C. | title = Henoch-Schönlein purpura: a review. | journal = Am Fam Physician | volume = 58 | issue = 2 | pages = 405-8, 411 | month = Aug | year = 1998 | doi =  | PMID = 9713395 }}</ref>
#[[Leukocytoclastic vasculitis]].<ref name=pmid9713395>{{Cite journal  | last1 = Kraft | first1 = DM. | last2 = Mckee | first2 = D. | last3 = Scott | first3 = C. | title = Henoch-Schönlein purpura: a review. | journal = Am Fam Physician | volume = 58 | issue = 2 | pages = 405-8, 411 | month = Aug | year = 1998 | doi =  | PMID = 9713395 }}</ref>
==Clinical features==
The classic triad is:<ref name=pmid19817340>{{Cite journal  | last1 = Reamy | first1 = BV. | last2 = Williams | first2 = PM. | last3 = Lindsay | first3 = TJ. | title = Henoch-Schönlein purpura. | journal = Am Fam Physician | volume = 80 | issue = 7 | pages = 697-704 | month = Oct | year = 2009 | doi =  | PMID = 19817340 | URL = http://www.aafp.org/link_out?pmid=19817340 }}</ref>
#Palpable purpura.
#Abdominal pain.
#Arthritis.
Mnemonic ''NAPA'':<ref>URL: [http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy]. Accessed on: 29 April 2012.</ref>
*'''N'''ephritis.
*'''A'''rthralgia/[[arthritis]].
*'''P'''alpable purpura.
*'''A'''bdominal pain.
Work-up - partial:
*ESR - high.
*Creatinine - high.
*CBC - platelets should be normal or high.
**Low platelets + purpura think [[thrombotic microangiopathies]] (e.g. [[TTP]], [[HUS]]).


==See also==
==See also==
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==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category: Cardiovascular pathology]]
[[Category: Cardiovascular pathology]]
[[Category: Pediatric pathology]]
[[Category: Pediatric pathology]]
[[Category: Diagnosis]]
[[Category: Diagnosis]]

Latest revision as of 17:07, 30 April 2012

Henoch-Schönlein purpura, abbreviated HSP, a disease that afflicts children.

Pathologically, it can be thought of as the combination of:

  1. IgA nephropathy.
  2. Leukocytoclastic vasculitis.[1]

Clinical features

The classic triad is:[2]

  1. Palpable purpura.
  2. Abdominal pain.
  3. Arthritis.

Mnemonic NAPA:[3]

  • Nephritis.
  • Arthralgia/arthritis.
  • Palpable purpura.
  • Abdominal pain.

Work-up - partial:

See also

References

  1. Kraft, DM.; Mckee, D.; Scott, C. (Aug 1998). "Henoch-Schönlein purpura: a review.". Am Fam Physician 58 (2): 405-8, 411. PMID 9713395.
  2. Reamy, BV.; Williams, PM.; Lindsay, TJ. (Oct 2009). "Henoch-Schönlein purpura.". Am Fam Physician 80 (7): 697-704. PMID 19817340.
  3. URL: http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy. Accessed on: 29 April 2012.