Difference between revisions of "Henoch–Schönlein purpura"
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'''Henoch-Schönlein purpura''' a disease that | '''Henoch-Schönlein purpura''', abbreviated '''HSP''', a disease that afflicts children. | ||
Pathologically, it can be thought of as the combination of: | Pathologically, it can be thought of as the combination of: | ||
#[[IgA nephropathy]]. | #[[IgA nephropathy]]. | ||
#[[Leukocytoclastic vasculitis]].<ref name=pmid9713395>{{Cite journal | last1 = Kraft | first1 = DM. | last2 = Mckee | first2 = D. | last3 = Scott | first3 = C. | title = Henoch-Schönlein purpura: a review. | journal = Am Fam Physician | volume = 58 | issue = 2 | pages = 405-8, 411 | month = Aug | year = 1998 | doi = | PMID = 9713395 }}</ref> | #[[Leukocytoclastic vasculitis]].<ref name=pmid9713395>{{Cite journal | last1 = Kraft | first1 = DM. | last2 = Mckee | first2 = D. | last3 = Scott | first3 = C. | title = Henoch-Schönlein purpura: a review. | journal = Am Fam Physician | volume = 58 | issue = 2 | pages = 405-8, 411 | month = Aug | year = 1998 | doi = | PMID = 9713395 }}</ref> | ||
==Clinical features== | |||
The classic triad is:<ref name=pmid19817340>{{Cite journal | last1 = Reamy | first1 = BV. | last2 = Williams | first2 = PM. | last3 = Lindsay | first3 = TJ. | title = Henoch-Schönlein purpura. | journal = Am Fam Physician | volume = 80 | issue = 7 | pages = 697-704 | month = Oct | year = 2009 | doi = | PMID = 19817340 | URL = http://www.aafp.org/link_out?pmid=19817340 }}</ref> | |||
#Palpable purpura. | |||
#Abdominal pain. | |||
#Arthritis. | |||
Mnemonic ''NAPA'':<ref>URL: [http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy]. Accessed on: 29 April 2012.</ref> | |||
*'''N'''ephritis. | |||
*'''A'''rthralgia/[[arthritis]]. | |||
*'''P'''alpable purpura. | |||
*'''A'''bdominal pain. | |||
Work-up - partial: | |||
*ESR - high. | |||
*Creatinine - high. | |||
*CBC - platelets should be normal or high. | |||
**Low platelets + purpura think [[thrombotic microangiopathies]] (e.g. [[TTP]], [[HUS]]). | |||
==See also== | ==See also== | ||
*[[Vasculitides]]. | *[[Vasculitides]]. | ||
*[[Medical kidney diseases]]. | *[[Medical kidney diseases]]. | ||
*[[Pediatric pathology]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category: Cardiovascular pathology]] | [[Category: Cardiovascular pathology]] | ||
[[Category: Pediatric pathology]] | [[Category: Pediatric pathology]] | ||
[[Category: Diagnosis]] | |||
Latest revision as of 17:07, 30 April 2012
Henoch-Schönlein purpura, abbreviated HSP, a disease that afflicts children.
Pathologically, it can be thought of as the combination of:
Clinical features
The classic triad is:[2]
- Palpable purpura.
- Abdominal pain.
- Arthritis.
Mnemonic NAPA:[3]
- Nephritis.
- Arthralgia/arthritis.
- Palpable purpura.
- Abdominal pain.
Work-up - partial:
- ESR - high.
- Creatinine - high.
- CBC - platelets should be normal or high.
- Low platelets + purpura think thrombotic microangiopathies (e.g. TTP, HUS).
See also
References
- ↑ Kraft, DM.; Mckee, D.; Scott, C. (Aug 1998). "Henoch-Schönlein purpura: a review.". Am Fam Physician 58 (2): 405-8, 411. PMID 9713395.
- ↑ Reamy, BV.; Williams, PM.; Lindsay, TJ. (Oct 2009). "Henoch-Schönlein purpura.". Am Fam Physician 80 (7): 697-704. PMID 19817340.
- ↑ URL: http://www.medicalmnemonics.com/cgi-bin/return_browse.cfm?browse=1&discipline=Rheumatology%20%2F%20Allergy. Accessed on: 29 April 2012.