Talk:Prostate gland

Prostate biopsy - 4 cores

Final

1. Prostate, right lateral, biopsy: - Negative for malignancy.

2. Prostate, right medial, biopsy: - Negative for malignancy.

3. Prostate, left medial, biopsy: - Negative for malignancy.

4. Prostate, left lateral, biopsy: - Negative for malignancy.

Prostate biopsy - 5 cores

Final

1. Prostate, right lateral, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 5% of tissue involved.

2. Prostate, right medial, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 40% of tissue involved.

3. Prostate nodule, left transition zone, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 40% of tissue involved.

4. Prostate, left medial, biopsy: - Negative for malignancy.

5. Prostate, left lateral, biopsy: - Negative for malignancy.

Prostate biopsy - 6 cores (apex, mid, base)

Final

1. Prostate, right apex peripheral, biopsy: - Benign prostate tissue.

2. Prostate, right mid, biopsy: - Benign prostatic tissue.

3. Prostate, right base, biopsy: - Benign prostatic tissue.

4. Prostate, left apex, biopsy: - Benign prostatic tissue.

5. Prostate, left mid, biopsy: - Benign prostatic tissue.

6. Prostate, left base, biopsy: - Benign prostatic tissue.

Prostate biopsy - 6 cores (base, mid, apex)

Final

1. Prostate, right base, biopsy: - Negative for malignancy.

2. Prostate, right mid, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 2/2 cores involved - 1st core: 80% of tissue, 2nd core: 55% of tissue; - approximately 70% of all tissue involved.

3. Prostate, right apex, biopsy: - Negative for malignancy.

4. Prostate, left base, biopsy: - Atypical small acinar proliferation.

5. Prostate, left mid, biopsy: - Negative for malignancy. - Acute and chronic inflammation.

6. Prostate, left apex, biopsy: - Negative for malignancy.

Prostate biopsy - 7 cores

Final

1. Prostate, right lateral, biopsy: - Negative for malignancy.

2. Prostate, right medial, biopsy: - Negative for malignancy. - Focal chronic inflammation.

3. Prostate, right transition zone, biopsy: - Negative for malignancy.

4. Prostate, mid, biopsy: - Negative for malignancy.

5. Prostate, left transition zone, biopsy: - Negative for malignancy. - Focal chronic inflammation.

6. Prostate, left medial, biopsy: - Negative for malignancy.

7. Prostate, left lateral, biopsy: - Atypical small acinar proliferation.

Prostate biopsy - 10 cores

Final

1. Prostate, right base peripheral, biopsy: - Benign prostate tissue.

2. Prostate, right mid peripheral, biopsy: - Benign prostate tissue.

3. Prostate, right apex peripheral, biopsy: - Benign prostate tissue.

4. Prostate, right base central, biopsy: - Benign prostate tissue.

5. Prostate, right mid central, biopsy: - Adenocarcinoma, Gleason score 6/10 (3+3); - 1/1 core involved; approximately 5% of tissue involved.

6. Prostate, left base peripheral, biopsy: - Atypical small acinar proliferation.

7. Prostate, left mid peripheral, biopsy: - Benign prostatic tissue.

8. Prostate, left apex peripheral, biopsy: - Benign prostatic tissue.

9. Prostate, left base central, biopsy: - Benign prostatic tissue.

10. Prostate, left mid central, biopsy: - Benign prostatic tissue.

Prostate biopsy - 12 cores

Final

1. Prostate, right base lateral, biopsy: - Benign prostate tissue.

2. Prostate, right base medial, biopsy: - Benign prostate tissue.

3. Prostate, right mid lateral, biopsy: - Benign prostate tissue.

4. Prostate, right mid medial, biopsy: - Benign fibromuscular tissue; - No prostatic glandular tissue present.

5. Prostate, right apex lateral, biopsy: - Benign prostate tissue.

6. Prostate, right apex medial, biopsy: - Benign prostate tissue.

7. Prostate, left base lateral, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 15% of tissue involved.

8. Prostate, left base medial, biopsy: - Adenocarcinoma, Gleason score 7/10 (4+3); - 1/1 core involved; approximately 5% of tissue involved; - Focal perineural invasion present.

9. Prostate, right mid lateral, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 50% of tissue involved.

10. Prostate, left mid medial, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 20% of tissue involved.

11. Prostate, left apex lateral, biopsy: - Benign prostate tissue.

12. Prostate, left apex medial, biopsy: - Benign prostate tissue.

Prostate biopsy - 12 cores - alternate

Final

1. PROSTATE, RIGHT LATERAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

2. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

3. PROSTATE, RIGHT LATERAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE.

4. PROSTATE, RIGHT MEDIAL MIDZONE, BIOPSY:
- BENIGN FIBROMUSCULAR TISSUE;
- NO PROSTATIC GLANDULAR TISSUE PRESENT.

5. PROSTATE, RIGHT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

6. PROSTATE, RIGHT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

7. PROSTATE, LEFT LATERAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 15% OF TISSUE INVOLVED.

8. PROSTATE, LEFT MEDIAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 7/10 (4+3);
- 1/1 CORE INVOLVED; APPROXIMATELY 5% OF TISSUE INVOLVED;
- FOCAL PERINEURAL INVASION PRESENT.

9. PROSTATE, LEFT LATERAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 50% OF TISSUE INVOLVED.

10. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 20% OF TISSUE INVOLVED.

11. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

12. PROSTATE, LEFT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

Soft tissue granulomas

J. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE;
- FOREIGN BODY-TYPE GRANULOMA, NONNECROTIZING, SEE COMMENT.

COMMENT:
The granulomas appear to be within the periprostatic soft tissue. They consist of
multinucleated (foreign body-type) giant cells, hyaline material and rare interspersed
neutrophils. No necrosis is identified. This finding may represent a reaction to displaced
epithelium from a previous procedure.

Weight

http://www.ncbi.nlm.nih.gov/pubmed/24053335 groups: <30, 30-50, >50

http://www.ncbi.nlm.nih.gov/pubmed/23795788 volume >80 mL

Inflammation

Micro

The sections show prostate cores with marked inflammation, that partially obscures the gland outlines. The inflammation is predominantly lymphocytic with a lesser amount of neutrophils and plasma cells. Eosinophils are not readily apparent. An isolated granuloma without necrosis is seen in one core.

The gland-to-stroma ratio is within normal limits. Basal cells are identified in the glands. Reactive nuclear changes are present. The gland architecture does not show changes characteristic of neoplasia.