Well-differentiated papillary mesothelial tumour: Difference between revisions
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| LMDDx = [[ovarian serous carcinoma]], [[serous borderline tumour of the ovary]], [[malignant mesothelioma]] especially ''papillary mesothelioma in situ'' | | LMDDx = [[ovarian serous carcinoma]], [[serous borderline tumour of the ovary]], [[malignant mesothelioma]] especially ''papillary mesothelioma in situ'' | ||
| Stains = | | Stains = | ||
| IHC = calretinin +ve, CK5/6 +ve, | | IHC = calretinin +ve, CK5/6 +ve, BAP1 retained (normal) | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 86: | Line 86: | ||
*Calretinin +ve. | *Calretinin +ve. | ||
*CK5/6 +ve. | *CK5/6 +ve. | ||
* | *[[BAP1]] retained (normal).<ref name=pmid35440764/> | ||
*MTAP retained (normal). | |||
**May not be sensitive.{{fact}} | |||
*[[Claudin-4]] -ve.{{fact}} | |||
==Sign out== | |||
<pre> | |||
A. Submitted as "Peritoneal Deposit", Excision: | |||
- Well-differentiated papillary mesothelial tumour, see comment. | |||
- NEGATIVE for malignancy. | |||
Comment: | |||
Well-differentiated papillary mesothelial tumour is a benign tumour. | |||
The tumour has retained (normal) BAP1 and retained MTAP staining. | |||
Claudin-4 and NF2F are NEGATIVE. | |||
</pre> | |||
==See also== | ==See also== | ||