Difference between revisions of "Serous carcinoma of the fallopian tube"

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'''Serous carcinoma of the fallopian tube''' is a [[serous carcinoma]] that arise from the [[Fallopian tube]]. These are thought to be important in the development of [[ovarian cancer]].<ref>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref>
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Serous carcinoma - fallopian tube -- high mag.jpg
| Width      =
| Caption    = Micrograph of fallopian tube serous carcinoma. [[H&E stain]].
| Synonyms  =
| Micro      =
| Subtypes  =
| LMDDx      = other [[serous carcinoma]]s (e.g. [[serous carcinoma of the ovary]]), [[serous tubal intraepithelial carcinoma]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[fallopian tube]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      = adnexal mass
| Endoscopy  =
| Prognosis  = usually poor
| Other      =
| ClinDDx    = [[ovarian cancer]], [[ovarian tumours]]
| Tx        =
}}
'''Serous carcinoma of the fallopian tube''' is a [[serous carcinoma]] that arise from the [[Fallopian tube]]. These are thought to be important in the development of [[ovarian cancer]].<ref name=pmid35159349>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref>
 
==General==
May be associated with germline mutations in:<ref name=pmid35159349>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref>  
*BRCA1.
*BRCA2.
*ATM.
*PALB2.
*[[BRIP1]].


==Microscopic==
==Microscopic==
:See ''[[serous carcinoma of the ovary]]''.
:See ''[[serous carcinoma of the ovary]]''.
DDx:
*Other [[serous carcinoma]]s, e.g. [[serous carcinoma of the ovary]].
*[[Serous tubal intraepithelial carcinoma]].
===Images===
<gallery>
Image: Serous carcinoma - fallopian tube -- extremely low mag.jpg | Serous carcinoma - extremely low mag.
Image: Serous carcinoma - fallopian tube -- very low mag.jpg | Serous carcinoma - very low mag.
Image: Serous carcinoma - fallopian tube -- low mag.jpg | Serous carcinoma - low mag.
Image: Serous carcinoma - fallopian tube -- intermed mag.jpg | Serous carcinoma - intermed. mag.
Image: Serous carcinoma - fallopian tube -- high mag.jpg | Serous carcinoma - high mag.
Image: Serous carcinoma - fallopian tube -- very high mag.jpg | Serous carcinoma - very high mag.
</gallery>


==See also==
==See also==
*[[Serous carcinoma]].
*[[Serous carcinoma]].
*[[Prophylactic bilateral salpingo-oophorectomy]].


==References==
==References==

Latest revision as of 16:21, 4 November 2024

Serous carcinoma of the fallopian tube
Diagnosis in short

Micrograph of fallopian tube serous carcinoma. H&E stain.
LM DDx other serous carcinomas (e.g. serous carcinoma of the ovary), serous tubal intraepithelial carcinoma
Site fallopian tube
Radiology adnexal mass
Prognosis usually poor
Clin. DDx ovarian cancer, ovarian tumours

Serous carcinoma of the fallopian tube is a serous carcinoma that arise from the Fallopian tube. These are thought to be important in the development of ovarian cancer.[1]

General

May be associated with germline mutations in:[1]

  • BRCA1.
  • BRCA2.
  • ATM.
  • PALB2.
  • BRIP1.

Microscopic

See serous carcinoma of the ovary.

DDx:

Images

  • Serous carcinoma - extremely low mag.

  • Serous carcinoma - very low mag.

  • Serous carcinoma - low mag.

  • Serous carcinoma - intermed. mag.

  • Serous carcinoma - high mag.

  • Serous carcinoma - very high mag.

See also

References

  1. ↑ 1.0 1.1 Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S (February 2022). "Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2". Cells 11 (3). doi:10.3390/cells11030539. PMC 8834207. PMID 35159349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834207/.
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