Difference between revisions of "Serous carcinoma of the fallopian tube"
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'''Serous carcinoma of the fallopian tube''' is a [[serous carcinoma]] that arise from the [[Fallopian tube]]. These are thought to be important in the development of [[ovarian cancer]].<ref>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref> | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Serous carcinoma - fallopian tube -- high mag.jpg | |||
| Width = | |||
| Caption = Micrograph of fallopian tube serous carcinoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = | |||
| Subtypes = | |||
| LMDDx = other [[serous carcinoma]]s (e.g. [[serous carcinoma of the ovary]]), [[serous tubal intraepithelial carcinoma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[fallopian tube]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = adnexal mass | |||
| Endoscopy = | |||
| Prognosis = usually poor | |||
| Other = | |||
| ClinDDx = [[ovarian cancer]], [[ovarian tumours]] | |||
| Tx = | |||
}} | |||
'''Serous carcinoma of the fallopian tube''' is a [[serous carcinoma]] that arise from the [[Fallopian tube]]. These are thought to be important in the development of [[ovarian cancer]].<ref name=pmid35159349>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref> | |||
==General== | |||
May be associated with germline mutations in:<ref name=pmid35159349>{{cite journal |authors=Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S |title=Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2 |journal=Cells |volume=11 |issue=3 |pages= |date=February 2022 |pmid=35159349 |pmc=8834207 |doi=10.3390/cells11030539 |url=}}</ref> | |||
*BRCA1. | |||
*BRCA2. | |||
*ATM. | |||
*PALB2. | |||
*[[BRIP1]]. | |||
==Microscopic== | |||
:See ''[[serous carcinoma of the ovary]]''. | |||
DDx: | |||
*Other [[serous carcinoma]]s, e.g. [[serous carcinoma of the ovary]]. | |||
*[[Serous tubal intraepithelial carcinoma]]. | |||
===Images=== | |||
<gallery> | |||
Image: Serous carcinoma - fallopian tube -- extremely low mag.jpg | Serous carcinoma - extremely low mag. | |||
Image: Serous carcinoma - fallopian tube -- very low mag.jpg | Serous carcinoma - very low mag. | |||
Image: Serous carcinoma - fallopian tube -- low mag.jpg | Serous carcinoma - low mag. | |||
Image: Serous carcinoma - fallopian tube -- intermed mag.jpg | Serous carcinoma - intermed. mag. | |||
Image: Serous carcinoma - fallopian tube -- high mag.jpg | Serous carcinoma - high mag. | |||
Image: Serous carcinoma - fallopian tube -- very high mag.jpg | Serous carcinoma - very high mag. | |||
</gallery> | |||
==See also== | ==See also== | ||
*[[Serous carcinoma]]. | *[[Serous carcinoma]]. | ||
*[[Prophylactic bilateral salpingo-oophorectomy]]. | |||
==References== | ==References== |
Latest revision as of 16:21, 4 November 2024
Serous carcinoma of the fallopian tube | |
---|---|
Diagnosis in short | |
Micrograph of fallopian tube serous carcinoma. H&E stain. | |
LM DDx | other serous carcinomas (e.g. serous carcinoma of the ovary), serous tubal intraepithelial carcinoma |
Site | fallopian tube |
| |
Radiology | adnexal mass |
Prognosis | usually poor |
Clin. DDx | ovarian cancer, ovarian tumours |
Serous carcinoma of the fallopian tube is a serous carcinoma that arise from the Fallopian tube. These are thought to be important in the development of ovarian cancer.[1]
General
May be associated with germline mutations in:[1]
- BRCA1.
- BRCA2.
- ATM.
- PALB2.
- BRIP1.
Microscopic
DDx:
- Other serous carcinomas, e.g. serous carcinoma of the ovary.
- Serous tubal intraepithelial carcinoma.
Images
See also
References
- ↑ 1.0 1.1 Samuel D, Diaz-Barbe A, Pinto A, Schlumbrecht M, George S (February 2022). "Hereditary Ovarian Carcinoma: Cancer Pathogenesis Looking beyond BRCA1 and BRCA2". Cells 11 (3). doi:10.3390/cells11030539. PMC 8834207. PMID 35159349. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8834207/.