Eosinophilic vacuolated tumour: Difference between revisions
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| Image = High-grade oncocytic renal tumour -- high mag.jpg | | Image = High-grade oncocytic renal tumour -- high mag.jpg | ||
| Width = | | Width = | ||
| Caption = Micrograph of | | Caption = Micrograph of an eosinophilic vacuolated tumour. [[H&E stain]]. | ||
| Synonyms = high-grade oncocytic tumour | | Synonyms = high-grade oncocytic tumour | ||
| Micro = abundant oncocytic cytoplasm with prominent intracytoplasmic vacuoles, | | Micro = abundant oncocytic cytoplasm with prominent intracytoplasmic vacuoles, | ||
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| IHC = PAX8 +ve, CD117 +ve, CD10 +ve, SDHB +ve, TFE3 -ve | | IHC = PAX8 +ve, CD117 +ve, CD10 +ve, SDHB +ve, TFE3 -ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = TSC1 or TSC2 mutation | ||
| IF = | | IF = | ||
| Gross = | | Gross = | ||
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*CD56 +ve.{{fact}} | *CD56 +ve.{{fact}} | ||
**Typically negative in [[renal oncocytoma]]. | **Typically negative in [[renal oncocytoma]]. | ||
==Molecular== | |||
*TSC1 or TSC2 mutation - see [[renal neoplasms with TSC/mTOR pathway mutations]]. | |||
==See also== | ==See also== | ||