Difference between revisions of "Atypical intraductal proliferation"
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'''Atypical intraductal proliferation''', abbreviated '''AIP''', is a [[waffle diagnosis]] in [[prostate]] pathology for lesions that are between [[high-grade prostatic intraepithelial neoplasia]] (HGPIN) and [[intraductal carcinoma of prostate]].<ref>{{cite journal |authors=Hickman RA, Yu H, Li J, Kong M, Shah RB, Zhou M, Melamed J, Deng FM |title=Atypical Intraductal Cribriform Proliferations of the Prostate Exhibit Similar Molecular and Clinicopathologic Characteristics as Intraductal Carcinoma of the Prostate |journal=Am J Surg Pathol |volume=41 |issue=4 |pages=550–556 |date=April 2017 |pmid=28009609 |doi=10.1097/PAS.0000000000000794 |url=}}</ref> | '''Atypical intraductal proliferation''', abbreviated '''AIP''', is a [[waffle diagnosis]] in [[prostate]] pathology for lesions that are between [[high-grade prostatic intraepithelial neoplasia]] (HGPIN) and [[intraductal carcinoma of prostate]].<ref>{{cite journal |authors=Hickman RA, Yu H, Li J, Kong M, Shah RB, Zhou M, Melamed J, Deng FM |title=Atypical Intraductal Cribriform Proliferations of the Prostate Exhibit Similar Molecular and Clinicopathologic Characteristics as Intraductal Carcinoma of the Prostate |journal=Am J Surg Pathol |volume=41 |issue=4 |pages=550–556 |date=April 2017 |pmid=28009609 |doi=10.1097/PAS.0000000000000794 |url=}}</ref> | ||
==Microscopic== | |||
Features: | |||
*Atypical prostatic glands - not fulfilling criteria for [[intraductal carcinoma of the prostate]]. | |||
*+/-[[Cribriform]] architecture. | |||
DDx:<ref name=pmid35758185>{{cite journal |authors=Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR |title=WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer |journal=Histopathology |volume=81 |issue=4 |pages=447–458 |date=October 2022 |pmid=35758185 |pmc=9542779 |doi=10.1111/his.14711 |url=}}</ref> | |||
*[[High-grade prostatic intraepithelial neoplasia]]. | |||
*[[Intraductal carcinoma of the prostate]]. | |||
==See also== | ==See also== | ||
*[[ASAP]]. | *[[ASAP]]. | ||
*[[Waffle diagnosis]]. | |||
==References== | ==References== | ||
Latest revision as of 17:22, 3 April 2024
Atypical intraductal proliferation, abbreviated AIP, is a waffle diagnosis in prostate pathology for lesions that are between high-grade prostatic intraepithelial neoplasia (HGPIN) and intraductal carcinoma of prostate.[1]
Microscopic
Features:
- Atypical prostatic glands - not fulfilling criteria for intraductal carcinoma of the prostate.
- +/-Cribriform architecture.
DDx:[2]
See also
References
- ↑ Hickman RA, Yu H, Li J, Kong M, Shah RB, Zhou M, Melamed J, Deng FM (April 2017). "Atypical Intraductal Cribriform Proliferations of the Prostate Exhibit Similar Molecular and Clinicopathologic Characteristics as Intraductal Carcinoma of the Prostate". Am J Surg Pathol 41 (4): 550–556. doi:10.1097/PAS.0000000000000794. PMID 28009609.
- ↑ Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR (October 2022). "WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer". Histopathology 81 (4): 447–458. doi:10.1111/his.14711. PMC 9542779. PMID 35758185. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542779/.