Difference between revisions of "BCL6"

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'''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]].  ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref>
'''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]].  ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref>


==Normal staining==
*Marks germinal centre cells.
Note:
*Usually paired with [[BCL2]] which is normally negative in germinal centres.
==Pathologic positive==
*[[Diffuse large B-cell lymphoma]] - may be negative.
*[[Burkitt lymphoma]].
*Others.


==See also==
==See also==
*[[BCL2]].
*[[BCL2]].
==References==
{{Reflist|1}}


[[Category:Immunohistochemistry]]
[[Category:Immunohistochemistry]]

Latest revision as of 15:56, 26 April 2022

BCL6 is a commonly used immunostain in hematopathology. BCL6 is gene and formally known as BCL6 transcription repressor.[1][2]

Normal staining

  • Marks germinal centre cells.

Note:

  • Usually paired with BCL2 which is normally negative in germinal centres.

Pathologic positive

See also

References