Difference between revisions of "BCL6"
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'''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]]. ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref> | '''BCL6''' is a commonly used [[immunostain]] in [[hematopathology]]. ''BCL6'' is gene and formally known as ''BCL6 transcription repressor''.<ref>URL: [https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001 https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001]. Accessed on: April 26, 2022.</ref><ref>{{OMIM|109565}}</ref> | ||
==Normal staining== | |||
*Marks germinal centre cells. | |||
Note: | |||
*Usually paired with [[BCL2]] which is normally negative in germinal centres. | |||
==Pathologic positive== | |||
*[[Diffuse large B-cell lymphoma]] - may be negative. | |||
*[[Burkitt lymphoma]]. | |||
*Others. | |||
==See also== | ==See also== | ||
*[[BCL2]]. | *[[BCL2]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category:Immunohistochemistry]] | [[Category:Immunohistochemistry]] | ||
Latest revision as of 15:56, 26 April 2022
BCL6 is a commonly used immunostain in hematopathology. BCL6 is gene and formally known as BCL6 transcription repressor.[1][2]
Normal staining
- Marks germinal centre cells.
Note:
- Usually paired with BCL2 which is normally negative in germinal centres.
Pathologic positive
- Diffuse large B-cell lymphoma - may be negative.
- Burkitt lymphoma.
- Others.
See also
- BCL2.
References
- ↑ URL: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1001. Accessed on: April 26, 2022.
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 109565