Difference between revisions of "SOX10"
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''' | '''SOX10''' is a common [[immunostain]]. | ||
==Positive== | ==Positive== | ||
*Metastatic [[malignant melanoma]] 119 +ve of 125 cases.<ref name=pmid25724000>{{cite journal |authors=Miettinen M, McCue PA, Sarlomo-Rikala M, Biernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF |title=Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors |journal=Am. J. Surg. Pathol. |volume=39 |issue=6 |pages=826–35 |date=June 2015 |pmid=25724000 |pmc=4431945 |doi=10.1097/PAS.0000000000000398 |url=}}</ref> | *Metastatic [[malignant melanoma]] 119 +ve of 125 cases.<ref name=pmid25724000>{{cite journal |authors=Miettinen M, McCue PA, Sarlomo-Rikala M, Biernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF |title=Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors |journal=Am. J. Surg. Pathol. |volume=39 |issue=6 |pages=826–35 |date=June 2015 |pmid=25724000 |pmc=4431945 |doi=10.1097/PAS.0000000000000398 |url=}}</ref> | ||
===Head and neck pathology=== | |||
Salivary gland tumours:<ref name=pmid27327192>{{cite journal |authors=Hsieh MS, Lee YH, Chang YL |title=SOX10-positive salivary gland tumors: a growing list, including mammary analogue secretory carcinoma of the salivary gland, sialoblastoma, low-grade salivary duct carcinoma, basal cell adenoma/adenocarcinoma, and a subgroup of mucoepidermoid carcinoma |journal=Hum Pathol |volume=56 |issue= |pages=134–42 |date=October 2016 |pmid=27327192 |doi=10.1016/j.humpath.2016.05.021 |url=}}</ref> | |||
*[[Secretory carcinoma of the salivary gland]]. | |||
*[[Sialoblastoma]]. | |||
*Low-grade [[salivary duct carcinoma]]. | |||
*[[Basal cell adenoma]]/[[basal cell adenocarcinoma]]. | |||
*[[Mucoepidermoid carcinoma]]. | |||
==References== | ==References== | ||
Latest revision as of 22:26, 9 October 2021
SOX10 is a common immunostain.
Positive
- Metastatic malignant melanoma 119 +ve of 125 cases.[1]
Head and neck pathology
Salivary gland tumours:[2]
- Secretory carcinoma of the salivary gland.
- Sialoblastoma.
- Low-grade salivary duct carcinoma.
- Basal cell adenoma/basal cell adenocarcinoma.
- Mucoepidermoid carcinoma.
References
- ↑ Miettinen M, McCue PA, Sarlomo-Rikala M, Biernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF (June 2015). "Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors". Am. J. Surg. Pathol. 39 (6): 826–35. doi:10.1097/PAS.0000000000000398. PMC 4431945. PMID 25724000. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431945/.
- ↑ Hsieh MS, Lee YH, Chang YL (October 2016). "SOX10-positive salivary gland tumors: a growing list, including mammary analogue secretory carcinoma of the salivary gland, sialoblastoma, low-grade salivary duct carcinoma, basal cell adenoma/adenocarcinoma, and a subgroup of mucoepidermoid carcinoma". Hum Pathol 56: 134–42. doi:10.1016/j.humpath.2016.05.021. PMID 27327192.