Sex cord-stromal tumours: Difference between revisions
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*[[Leydig cell tumour]]. | *[[Leydig cell tumour]]. | ||
*[[Sertoli cell tumour]]. | *[[Sertoli cell tumour]]. | ||
*Primary signet ring stromal tumour.<ref name=pmid28739499>{{cite journal |authors=Michalova K, Michal M, Kazakov DV, Sedivcova M, Hes O, Hadravsky L, Agaimy A, Tretiakova M, Bacchi C, Hartmann A, Kuroda N, Bulimbasic S, Coric M, Antic T, Michal M |title=Primary signet ring stromal tumor of the testis: a study of 13 cases indicating their phenotypic and genotypic analogy to pancreatic solid pseudopapillary neoplasm |journal=Hum Pathol |volume=67 |issue= |pages=85–93 |date=September 2017 |pmid=28739499 |doi=10.1016/j.humpath.2017.07.010 |url=}}</ref> | |||
==Ovarian== | ==Ovarian== | ||
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==Mixed== | ==Mixed== | ||
*[[Gynandroblastoma]].<ref name=pmid19332247>{{Cite journal | last1 = Koulouris | first1 = CR. | last2 = Penson | first2 = RT. | title = Ovarian stromal and germ cell tumors. | journal = Semin Oncol | volume = 36 | issue = 2 | pages = 126-36 | month = Apr | year = 2009 | doi = 10.1053/j.seminoncol.2008.12.004 | PMID = 19332247 }}</ref> | *[[Gynandroblastoma]].<ref name=pmid19332247>{{Cite journal | last1 = Koulouris | first1 = CR. | last2 = Penson | first2 = RT. | title = Ovarian stromal and germ cell tumors. | journal = Semin Oncol | volume = 36 | issue = 2 | pages = 126-36 | month = Apr | year = 2009 | doi = 10.1053/j.seminoncol.2008.12.004 | PMID = 19332247 }}</ref> | ||
==IHC== | |||
*Steroidogenic factor 1 (SF1) +ve.<ref name=pmid37621390>{{cite journal |authors=Satariano M, Losinski E, Lane J, Wegryn J |title=Adult-type granulosa cell tumor of the testis: A case report and review of the literature |journal=Urol Case Rep |volume=50 |issue= |pages=102532 |date=September 2023 |pmid=37621390 |pmc=10445446 |doi=10.1016/j.eucr.2023.102532 |url=}}</ref> | |||
*Calretinin +ve. | |||
*Inhibin A +ve. | |||
*SALL4 -ve. | |||
**Positive in (most) [[germ cell tumours]]. | |||
*FH -ve/+ve. | |||
**A ''fumarate hydratase-deficient testicular sex cord-stromal tumour'' has been proposed.<ref>{{cite journal |vauthors=Acosta AM, Colecchia M, Berney DM |title=Fumarate hydratase-deficient testicular sex cord-stromal tumour (FH-TSCST): proposal for reclassification of a subset of Leydig cell tumours with distinct molecular and clinicopathologic features |journal=Histopathology |volume=82 |issue=4 |pages=646–647 |date=March 2023 |pmid=36592067 |doi=10.1111/his.14859 |url=}}</ref> | |||
==See also== | ==See also== | ||