Talk:Prostate cancer grading: Difference between revisions
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Gleason pattern 3 represents 15% of the cancer, and Gleason pattern 4 represents 85% of the cancer. The Gleason pattern 4 is concentrated in a nodule at the apex; the overall grade is based on this (separate) nodule. | Gleason pattern 3 represents 15% of the cancer, and Gleason pattern 4 represents 85% of the cancer. The Gleason pattern 4 is concentrated in a nodule at the apex; the overall grade is based on this (separate) nodule. | ||
Is grading of the index (dominant) nodule in prostate cancer of greater prognostic significance than global grading? | |||
https://doi.org/10.1016/j.pathol.2023.08.005 | |||
Index grade group is superior to composite grade group for prediction of biochemical recurrence following radical prostatectomy | |||
https://doi.org/10.1016/j.pathol.2022.10.012 | |||
== Poorly formed glands - Gleason 4 == | == Poorly formed glands - Gleason 4 == | ||
https://www.ncbi.nlm.nih.gov/pubmed/26099009 | https://www.ncbi.nlm.nih.gov/pubmed/26099009 | ||
== Update == | |||
*ISUP https://pubmed.ncbi.nlm.nih.gov/31279442/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382533/ | |||
*GUPS https://pubmed.ncbi.nlm.nih.gov/32589068/ | |||