Difference between revisions of "Traumatic ulcerative granuloma with stromal eosinophilia"

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Traumatic ulcerative granuloma with stromal eosinophils - alt -- extremely low mag.jpg
| Width      =
| Caption    = TUGSE. [[H&E stain]]. (WC/Nephron)
| Synonyms  =
| Micro      = stromal [[eosinophil]]s and lymphocytes, ulceration.
| Subtypes  =
| LMDDx      = [[diffuse large B-cell lymphoma]], [[lobular capillary hemangioma]] (pyogenic granuloma), [[granulation tissue]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[head and neck pathology|head and neck]] - usually tongue
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Traumatic ulcerative granuloma with stromal eosinophilia''', abbreviated '''TUGSE''', is a benign lesion of the oral mucosa.<ref name=pmid16938660>{{Cite journal  | last1 = Hirshberg | first1 = A. | last2 = Amariglio | first2 = N. | last3 = Akrish | first3 = S. | last4 = Yahalom | first4 = R. | last5 = Rosenbaum | first5 = H. | last6 = Okon | first6 = E. | last7 = Kaplan | first7 = I. | title = Traumatic ulcerative granuloma with stromal eosinophilia: a reactive lesion of the oral mucosa. | journal = Am J Clin Pathol | volume = 126 | issue = 4 | pages = 522-9 | month = Oct | year = 2006 | doi = 10.1309/AFHA406GBT0N2Y64 | PMID = 16938660 }}</ref>
'''Traumatic ulcerative granuloma with stromal eosinophilia''', abbreviated '''TUGSE''', is a benign lesion of the oral mucosa.<ref name=pmid16938660>{{Cite journal  | last1 = Hirshberg | first1 = A. | last2 = Amariglio | first2 = N. | last3 = Akrish | first3 = S. | last4 = Yahalom | first4 = R. | last5 = Rosenbaum | first5 = H. | last6 = Okon | first6 = E. | last7 = Kaplan | first7 = I. | title = Traumatic ulcerative granuloma with stromal eosinophilia: a reactive lesion of the oral mucosa. | journal = Am J Clin Pathol | volume = 126 | issue = 4 | pages = 522-9 | month = Oct | year = 2006 | doi = 10.1309/AFHA406GBT0N2Y64 | PMID = 16938660 }}</ref>


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*[[Diffuse large B-cell lymphoma]].
*[[Diffuse large B-cell lymphoma]].
*[[Lobular capillary hemangioma]].
*[[Lobular capillary hemangioma]].
*[[Granulation tissue]].
===Images===
<gallery>
Image: Traumatic ulcerative granuloma with stromal eosinophils -- extremely low mag.jpg |TUGSE - extremely low mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils -- very low mag.jpg |TUGSE - very low mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils -- low mag.jpg |TUGSE - low mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils -- intermed mag.jpg |TUGSE - intermed. mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils - alt -- intermed mag.jpg |TUGSE - intermed. mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils -- high mag.jpg |TUGSE - high mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils - alt -- high mag.jpg |TUGSE - high mag. (WC)
Image: Traumatic ulcerative granuloma with stromal eosinophils -- very high mag.jpg |TUGSE - very high mag. (WC)
</gallery>


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Latest revision as of 04:40, 5 January 2017

Traumatic ulcerative granuloma with stromal eosinophilia
Diagnosis in short

TUGSE. H&E stain. (WC/Nephron)
LM stromal eosinophils and lymphocytes, ulceration.
LM DDx diffuse large B-cell lymphoma, lobular capillary hemangioma (pyogenic granuloma), granulation tissue
Site head and neck - usually tongue
Prevalence uncommon
Prognosis benign

Traumatic ulcerative granuloma with stromal eosinophilia, abbreviated TUGSE, is a benign lesion of the oral mucosa.[1]

It is also known as traumatic ulcerative granuloma with stromal eosinphils, eosinophilic ulcer of tongue and traumatic eosinophilic granuloma.

General

  • Benign.
  • Obscure lesion that is not widely known.[2]

Gross

  • Usually tongue ~ 2/3 of cases.[3]

Microscopic

Features:[2]

  • Stromal eosinophils and lymphocytes.
  • Ulceration.

DDx:

Images

  • TUGSE - extremely low mag. (WC)

  • TUGSE - very low mag. (WC)

  • TUGSE - low mag. (WC)

  • TUGSE - intermed. mag. (WC)

  • TUGSE - intermed. mag. (WC)

  • TUGSE - high mag. (WC)

  • TUGSE - high mag. (WC)

  • TUGSE - very high mag. (WC)

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Lesion, Right Tongue, Excisional Biopsy:
     - Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE), see comment.
     - NEGATIVE for malignancy.

Comment:
TUGSE is an uncommon benign lesion of the oral mucosa.

See also

References

  1. ↑ Hirshberg, A.; Amariglio, N.; Akrish, S.; Yahalom, R.; Rosenbaum, H.; Okon, E.; Kaplan, I. (Oct 2006). "Traumatic ulcerative granuloma with stromal eosinophilia: a reactive lesion of the oral mucosa.". Am J Clin Pathol 126 (4): 522-9. doi:10.1309/AFHA406GBT0N2Y64. PMID 16938660.
  2. ↑ 2.0 2.1 Sarangarajan, R.; Vaishnavi Vedam, VK.; Sivadas, G.; Sarangarajan, A.; Meera, S. (Aug 2015). "Traumatic ulcerative granuloma with stromal eosinophilia - Mystery of pathogenesis revisited.". J Pharm Bioallied Sci 7 (Suppl 2): S420-3. doi:10.4103/0975-7406.163474. PMID 26538890.
  3. ↑ Shen, WR.; Chang, JY.; Wu, YC.; Cheng, SJ.; Chen, HM.; Wang, YP. (Sep 2015). "Oral traumatic ulcerative granuloma with stromal eosinophilia: A clinicopathological study of 34 cases.". J Formos Med Assoc 114 (9): 881-5. doi:10.1016/j.jfma.2013.09.012. PMID 24269143.
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