Vasculitides: Difference between revisions

Jump to navigation Jump to search
← Older edit
Michael (talk | contribs)
49,358 edits
Michael (talk | contribs)
49,358 edits
 
(5 intermediate revisions by the same user not shown)
Line 8: Line 8:
*Polyarteritis nodosa (PAN).
*Polyarteritis nodosa (PAN).
*Microscopic polyangiitis.
*Microscopic polyangiitis.
*Wegener's granulomatosis.
*Granulomatosis with polyangiitis (Wegener's granulomatosis).
*Predominantly cutaneous vasculitis.
*Predominantly cutaneous vasculitis.
*Giant cell arteritis (GCA).
*Giant cell arteritis (GCA).
Line 24: Line 24:
*Essential cryoglobulinemic vasculitis.
*Essential cryoglobulinemic vasculitis.
*ANCA-associated:
*ANCA-associated:
**[[Wegener's granulomatosis]] (c-ANCA > p-ANCA).
**[[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) - c-ANCA > p-ANCA.
**[[Churg-Strauss syndrome]] (50% ANCA +ve).
**[[Eosinophilic granulomatosis with polyangiitis]] (Churg-Strauss syndrome) - 50% ANCA +ve.
**[[Microscopic polyangiitis]] (usually p-ANCA).
**[[Microscopic polyangiitis]] - usually p-ANCA.


Notes:
Notes:
Line 46: Line 46:
*Giant cell arteritis.
*Giant cell arteritis.
*Takayasu arteritis.
*Takayasu arteritis.
*Churg-Strauss disease.
*Eosinophilic granulomatosis with polyangiitis (Churg-Strauss disease).
*Wegener’s granulomatosis.
*Granulomatosis with polyangiitis (Wegener’s granulomatosis).


Note:
Note:
Line 121: Line 121:


==Granulomatosis with polyangiitis==
==Granulomatosis with polyangiitis==
*[[AKA]] ''Wegener granulomatosis''.
:Previously known as ''Wegener granulomatosis''.
{{Main|Granulomatosis with polyangiitis}}
{{Main|Granulomatosis with polyangiitis}}


==Churg-Strauss syndrome==
==Eosinophilic granulomatosis with polyangiitis==
*Abbreviated ''CSS''.
:Previously known as ''Churg-Strauss syndrome'' and ''Churg-Strauss disease''.
*AKA ''allergic granulomatous angiitis''.<ref name=emedicine333492>[http://emedicine.medscape.com/article/333492-overview http://emedicine.medscape.com/article/333492-overview]</ref>
{{Main|Eosinophilic granulomatosis with polyangiitis}}
*[[AKA]] ''Churg-Strauss disease''.


===General===
Defining features - memory device ''GAFE'':
*'''G'''ranulomata.
*'''A'''sthma.
*'''F'''ever.
*'''E'''osinophilia.
Notes:
*Similar to ''[[Wegener's granulomatosis]]'' (classically c-ANCA +ve) and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>
===Microscopic===
Features:
*Small vessel [[vasculitis]].
*Abundant eosinophils.
*[[Granuloma]]s.
DDx:
*Eosinophilic vasculitis associated with a [[connective tissue disease]].<ref name=pmid8708015>{{Cite journal  | last1 = Chen | first1 = KR. | last2 = Su | first2 = WP. | last3 = Pittelkow | first3 = MR. | last4 = Conn | first4 = DL. | last5 = George | first5 = T. | last6 = Leiferman | first6 = KM. | title = Eosinophilic vasculitis in connective tissue disease. | journal = J Am Acad Dermatol | volume = 35 | issue = 2 Pt 1 | pages = 173-82 | month = Aug | year = 1996 | doi =  | PMID = 8708015 }}</ref>
====Images====
<gallery>
Image:Churg-Strauss_syndrome_-_high_mag.jpg |CSS - high mag. (WC)
Image:Churg-Strauss_syndrome_-_very_high_mag.jpg |CSS - very high mag. (WC)
</gallery>
=Medium vessel vasculitides=
=Medium vessel vasculitides=
The follow section has information specific to the individual types of medium vessel vasculitis.
The follow section has information specific to the individual types of medium vessel vasculitis.
Retrieved from "https://librepathology.org/wiki/Vasculitides"