Difference between revisions of "CD117"
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'''CD117''' is common [[immunostain]]. | '''CD117''' is common [[immunostain]]. | ||
==Normal tissue positive== | |||
*Mast cells.<ref name=pmid16082245>{{cite journal |authors=Miettinen M, Lasota J |title=KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation |journal=Appl Immunohistochem Mol Morphol |volume=13 |issue=3 |pages=205–20 |date=September 2005 |pmid=16082245 |doi=10.1097/01.pai.0000173054.83414.22 |url=}}</ref> | |||
*Cajal cells.<ref name=pmid16082245/> | |||
*Germ cells.<ref name=pmid16082245/> | |||
*Melanocytes.<ref name=pmid16082245/> | |||
==Positive== | ==Positive== | ||
*[[Gastrointestinal stromal tumour]]. | *[[Gastrointestinal stromal tumour]]. | ||
*[[Seminoma]]. | *[[Seminoma]].<ref name=pmid24832161>{{cite journal |author=Ulbright TM, Tickoo SK, Berney DM, Srigley JR |title=Best practices recommendations in the application of immunohistochemistry in testicular tumors: report from the international society of urological pathology consensus conference |journal=Am. J. Surg. Pathol. |volume=38 |issue=8 |pages=e50–9 |year=2014 |month=August |pmid=24832161 |doi=10.1097/PAS.0000000000000233 |url=}}</ref> | ||
*[[Renal oncocytoma]]. | *[[Renal oncocytoma]]. | ||
*[[Chromophobe renal cell carcinoma]]. | *[[Chromophobe renal cell carcinoma]]. | ||
Latest revision as of 16:31, 13 January 2022
CD117 is common immunostain.
Normal tissue positive
Positive
- Gastrointestinal stromal tumour.
- Seminoma.[2]
- Renal oncocytoma.
- Chromophobe renal cell carcinoma.
- Renal hybrid oncocytic/chromophobe tumour.
- Adenoid cystic carcinoma.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Miettinen M, Lasota J (September 2005). "KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation". Appl Immunohistochem Mol Morphol 13 (3): 205–20. doi:10.1097/01.pai.0000173054.83414.22. PMID 16082245.
- ↑ Ulbright TM, Tickoo SK, Berney DM, Srigley JR (August 2014). "Best practices recommendations in the application of immunohistochemistry in testicular tumors: report from the international society of urological pathology consensus conference". Am. J. Surg. Pathol. 38 (8): e50–9. doi:10.1097/PAS.0000000000000233. PMID 24832161.