Desmoplastic small round cell tumour: Difference between revisions

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Jensflorian (talk | contribs)
→IHC: WT nuclear + CAM5.2
 
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*Typically retroperitoneal.
*Typically retroperitoneal.
*Poor prognosis.
*Poor prognosis.
==Clinics==
*Rare cases in the CNS reported.


==Microscopic==
==Microscopic==
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Features:
Features:
*[[AE1/AE3]] +ve.
*[[AE1/AE3]] +ve.
*Desmin +ve.  
*CAM5.2 usu -ve.
*Desmin +ve (strongly).  
*[[EMA]] +ve.
*[[EMA]] +ve.
*Actin -ve.
*Actin -ve.
*WT1 (N-terminal) -ve.
*[[WT-1]] (N-terminal) -ve.
*WT1 (C-terminal) +ve.
*[[WT-1]] (C-terminal) +ve (nuclear staining).
*CD57 +ve.
*CD57 +ve.
*[[Synaptophysin]] focal, patchy +ve.


==Molecular==
==Molecular==
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[[Category:Soft tissue lesions]]
[[Category:Soft tissue lesions]]
[[Category:Neuropathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]