Difference between revisions of "Endocrine atypia"
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[[Image:Endocrine atypia in thyroid - 2 -- very high mag.jpg|thumb|right|Endocrine atypia in the thyroid. (WC/Nephron)]] | [[Image:Endocrine atypia in thyroid - 2 -- very high mag.jpg|thumb|right|Endocrine atypia in the thyroid. (WC/Nephron)]] | ||
'''Endocrine atypia''' refers to | '''Endocrine atypia''' refers to [[nuclear atypia]] seen in normal and benign endocrine organs and is relatively common.<ref name=pmid21455204>{{Cite journal | last1 = DeLellis | first1 = RA. | title = Parathyroid tumors and related disorders. | journal = Mod Pathol | volume = 24 Suppl 2 | issue = | pages = S78-93 | month = Apr | year = 2011 | doi = 10.1038/modpathol.2010.132 | PMID = 21455204 }}</ref> | ||
As [[nuclear atypia]] is considered a benign finding in endocrine organs, [[malignant]] diagnoses can be challenging or near impossible in these organs.<ref name=pmid27160525>{{Cite journal | last1 = Christakis | first1 = I. | last2 = Bussaidy | first2 = N. | last3 = Clarke | first3 = C. | last4 = Kwatampora | first4 = LJ. | last5 = Warneke | first5 = CL. | last6 = Silva | first6 = AM. | last7 = Williams | first7 = MD. | last8 = Grubbs | first8 = EG. | last9 = Lee | first9 = JE. | title = Differentiating Atypical Parathyroid Neoplasm from Parathyroid Cancer. | journal = Ann Surg Oncol | volume = | issue = | pages = | month = May | year = 2016 | doi = 10.1245/s10434-016-5248-6 | PMID = 27160525 }}</ref> | As [[nuclear atypia]] is considered a benign finding in endocrine organs, [[malignant]] diagnoses can be challenging or near impossible to render in these organs.<ref name=pmid27160525>{{Cite journal | last1 = Christakis | first1 = I. | last2 = Bussaidy | first2 = N. | last3 = Clarke | first3 = C. | last4 = Kwatampora | first4 = LJ. | last5 = Warneke | first5 = CL. | last6 = Silva | first6 = AM. | last7 = Williams | first7 = MD. | last8 = Grubbs | first8 = EG. | last9 = Lee | first9 = JE. | title = Differentiating Atypical Parathyroid Neoplasm from Parathyroid Cancer. | journal = Ann Surg Oncol | volume = | issue = | pages = | month = May | year = 2016 | doi = 10.1245/s10434-016-5248-6 | PMID = 27160525 }}</ref> | ||
Malignant diagnoses can be especially challenging in: | Malignant diagnoses can be especially challenging in the: | ||
*[[Adrenal gland]]. | *[[Adrenal gland]] - see [[pheochromocytoma]]. | ||
*[[Parathyroid gland]]. | *[[Parathyroid gland]] - see [[parathyroid carcinoma]].<ref name=pmid21455204/> | ||
==See also== | ==See also== | ||
Latest revision as of 12:33, 7 June 2016
Endocrine atypia refers to nuclear atypia seen in normal and benign endocrine organs and is relatively common.[1]
As nuclear atypia is considered a benign finding in endocrine organs, malignant diagnoses can be challenging or near impossible to render in these organs.[2]
Malignant diagnoses can be especially challenging in the:
See also
References
- ↑ 1.0 1.1 DeLellis, RA. (Apr 2011). "Parathyroid tumors and related disorders.". Mod Pathol 24 Suppl 2: S78-93. doi:10.1038/modpathol.2010.132. PMID 21455204.
- ↑ Christakis, I.; Bussaidy, N.; Clarke, C.; Kwatampora, LJ.; Warneke, CL.; Silva, AM.; Williams, MD.; Grubbs, EG. et al. (May 2016). "Differentiating Atypical Parathyroid Neoplasm from Parathyroid Cancer.". Ann Surg Oncol. doi:10.1245/s10434-016-5248-6. PMID 27160525.