Difference between revisions of "Meckel diverticulum"

From Libre Pathology
Jump to navigation Jump to search
(split out)
 
(12 intermediate revisions by 2 users not shown)
Line 1: Line 1:
'''Meckel diverticulum''' (also '''Meckel's diverticulum'''), is congenital structure of the distal [[small bowel]] that occasionally gets inflamed and may present with appendicitis-like symptoms.
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Meckel%27s_Diverticulum_AFIP.jpg
| Width      =
| Caption    = Gross image of a Meckel diverticulum. (AFIP/WC)
| Synonyms  =
| Micro      = small bowel mucosa, +/-gastric mucosa (foveolar epithelium, oxyntic mucosa), +/-pancreatic epithelium
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = small bowel outpouching on antemesenteric aspect ~5 cm long, ~60 cm from the [[ileocecal valve]]
| Grossing  =
| Staging    =
| Site      = [[small intestine]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  = abdominal pain
| Prevalence = uncommon ~2% of population
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    = [[acute appendicitis]], other causes of abdominal pain
| Tx        = surgical removal
}}
'''Meckel diverticulum''' (also '''Meckel's diverticulum'''), is congenital structure of the distal [[small bowel]] that occasionally gets inflamed and may present with [[acute appendicitis]]-like symptoms.


==General==
==General==
Line 19: Line 51:
*Antimesenteric attachement, i.e. a ''Meckel's diverticulum'' hangs off the side opposite of the mesentery.  
*Antimesenteric attachement, i.e. a ''Meckel's diverticulum'' hangs off the side opposite of the mesentery.  


Image:
===Image===
*[http://commons.wikimedia.org/wiki/File:Meckel%27s_Diverticulum_AFIP.jpg Meckel diverticulum - (AFIP/WC)].
<gallery>
Image:Meckel%27s_Diverticulum_AFIP.jpg | Meckel diverticulum. (AFIP/WC)
</gallery>


==Microscopic==
==Microscopic==
Line 32: Line 66:


===Images===
===Images===
*[http://radiographics.rsna.org/content/24/2/565/F12.expansion.html Gastric foveolar epithelium in a MD (radiographics.rsna.org)].
 
*[http://radiographics.rsna.org/content/24/2/565/F15.expansion.html Gastric glands in a MD (radiographics.rsna.org)].
*[http://radiographics.rsna.org/content/24/2/565.long Pancreatic glands and gastric mucosa in a MD (radiographics.rsna.org)].
*[http://radiographics.rsna.org/content/24/2/565.long Pancreatic glands in a MD (radiographics.rsna.org)].
 
==Sign out==
<pre>
Small bowel with Meckel's diverticulum, Excision:
    - Benign small bowel diverticulum with focal active inflammation and reactive
      lymphoid hyperplasia at tip, compatible with clinical impression of
      inflamed Meckel's diverticulum.  
    - Unremarkable small bowel wall at resection margin.
</pre>


==See also==
==See also==
Line 43: Line 85:


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Gastrointestinal pathology]]

Latest revision as of 16:23, 10 April 2023

Meckel diverticulum (also Meckel's diverticulum), is congenital structure of the distal small bowel that occasionally gets inflamed and may present with acute appendicitis-like symptoms.

Meckel diverticulum
Diagnosis in short

Gross image of a Meckel diverticulum. (AFIP/WC)

LM small bowel mucosa, +/-gastric mucosa (foveolar epithelium, oxyntic mucosa), +/-pancreatic epithelium
Gross small bowel outpouching on antemesenteric aspect ~5 cm long, ~60 cm from the ileocecal valve
Site small intestine

Symptoms abdominal pain
Prevalence uncommon ~2% of population
Prognosis benign
Clin. DDx acute appendicitis, other causes of abdominal pain
Treatment surgical removal

General

  • Most common congenital anomaly of the gastrointestinal tract.[1]
    • Remnant of the omphalomesenteric duct - a connection of the yolk sac and midgut.

The rule of 2s:

  • 2 feet from the terminal ileum
  • 2% of the population
  • 2% symptomatic.
  • 2 inches long.
  • 2 year old.
  • 2 types of epithelium - gastric and pancreatic.

Main clinical DDx of a symptomatic Meckel diverticulum:

Gross

  • Antimesenteric attachement, i.e. a Meckel's diverticulum hangs off the side opposite of the mesentery.

Image

Microscopic

Features:[1]

  • Small bowel mucosa.
  • +/-Gastric mucosa:
    • Foveolar epithelium: champagne flute-like columnar epithelium.
    • Oxyntic mucosa: parietal cells (pink) and chief cells (purple).
  • +/-Pancreatic epithelium:
    • Pancreatic acini.

Images

Sign out

Small bowel with Meckel's diverticulum, Excision:
    - Benign small bowel diverticulum with focal active inflammation and reactive 
      lymphoid hyperplasia at tip, compatible with clinical impression of 
      inflamed Meckel's diverticulum. 
    - Unremarkable small bowel wall at resection margin.

See also

References

  1. 1.0 1.1 Levy, AD.; Hobbs, CM.. "From the archives of the AFIP. Meckel diverticulum: radiologic features with pathologic Correlation.". Radiographics 24 (2): 565-87. doi:10.1148/rg.242035187. PMID 15026601.