Pseudomelanosis coli: Difference between revisions
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| Caption = Pseudomelanosis coli. [[H&E stain]]. | | Caption = Pseudomelanosis coli. [[H&E stain]]. | ||
| Synonyms = melanosis coli | |||
| Micro = brown granular pigment in the lamina propria, abundant | | Micro = brown granular pigment in the lamina propria, abundant | ||
| Subtypes = | | Subtypes = | ||
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==General== | ==General== | ||
*''Not melanin'' as the name ''melanosis coli'' suggests; it is actually lipofuscin (in macrophages).<ref name=pmid18666316>{{cite journal |author=Freeman HJ |title="Melanosis" in the small and large intestine |journal=World J. Gastroenterol. |volume=14 |issue=27 |pages=4296-9 |year=2008 |month=July |pmid=18666316 |doi= |url=http://www.wjgnet.com/1007-9327/14/4296.asp}}</ref> | *''Not melanin'' as the name ''melanosis coli'' suggests; it is actually [[lipofuscin]] (in macrophages).<ref name=pmid18666316>{{cite journal |author=Freeman HJ |title="Melanosis" in the small and large intestine |journal=World J. Gastroenterol. |volume=14 |issue=27 |pages=4296-9 |year=2008 |month=July |pmid=18666316 |doi= |url=http://www.wjgnet.com/1007-9327/14/4296.asp}}</ref> | ||
*Endoscopist may see brown pigmentation of mucosa and suspect the diagnosis. | *Endoscopist may see brown pigmentation of mucosa and suspect the diagnosis. | ||
*Presence may lead to endoscopic misinterpretation of colitis severity.<ref name=pmid21375218>{{Cite journal | last1 = Zapatier | first1 = JA. | last2 = Schneider | first2 = A. | last3 = Parra | first3 = JL. | title = Overestimation of ulcerative colitis due to melanosis coli. | journal = Acta Gastroenterol Latinoam | volume = 40 | issue = 4 | pages = 351-3 | month = Dec | year = 2010 | doi = | PMID = 21375218 }}</ref> | *Presence may lead to endoscopic misinterpretation of colitis severity.<ref name=pmid21375218>{{Cite journal | last1 = Zapatier | first1 = JA. | last2 = Schneider | first2 = A. | last3 = Parra | first3 = JL. | title = Overestimation of ulcerative colitis due to melanosis coli. | journal = Acta Gastroenterol Latinoam | volume = 40 | issue = 4 | pages = 351-3 | month = Dec | year = 2010 | doi = | PMID = 21375218 }}</ref> | ||
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Note: | Note: | ||
*May also been seen in the [[small intestine]].<ref name=pmid18666316>{{ | *May also been seen in the [[small intestine]].<ref name=pmid18666316>{{cite journal |author=Freeman HJ |title="Melanosis" in the small and large intestine |journal=World J. Gastroenterol. |volume=14 |issue=27 |pages=4296-9 |year=2008 |month=July |pmid=18666316 |doi= |url=http://www.wjgnet.com/1007-9327/14/4296.asp}}</ref> | ||
===Endoscopic image=== | ===Endoscopic image=== | ||
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*[[Gastrointestinal pathology]]. | *[[Gastrointestinal pathology]]. | ||
*[[Colon]]. | *[[Colon]]. | ||
*[[Small bowel pseudomelanosis]]. | |||
==References== | ==References== | ||