Difference between revisions of "Standarized uptake value"
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'''Standardized uptake value''', abbreviated '''SUV''', is a semi-quantitative measure in PET | '''Standardized uptake value''', abbreviated '''SUV''', is a semi-quantitative measure in [[PET scan]]s. | ||
:<math>SUV = \frac {c(t)}{injected\ dose(t_0) \quad / \quad body\ weight}</math> | :<math>SUV = \frac {c(t)}{injected\ dose(t_0) \quad / \quad body\ weight}</math> | ||
==Non-small cell lung cancer== | ==Non-small cell lung cancer== | ||
*The SUV of fluorine-18 fluorodeoxyglucose of the primary tumour is a predictor of lymph node metastases in multivariate analysis.<ref name=pmid24535381>{{Cite journal | last1 = Xu | first1 = ZQ. | last2 = Xie | first2 = LJ. | last3 = Fan | first3 = W. | last4 = Duan | first4 = XB. | last5 = Cheng | first5 = MH. | title = Risk factors for mediastinal lymph node metastasis in non-small-cell lung cancer by PET/CT. | journal = Nucl Med Commun | volume = 35 | issue = 5 | pages = 466-71 | month = May | year = 2014 | doi = 10.1097/MNM.0000000000000077 | PMID = 24535381 }}</ref> | {{Main|Non-small cell lung cancer}} | ||
*The SUV of fluorine-18 fluorodeoxyglucose of the primary tumour is a predictor of lymph node metastases in a multivariate analysis.<ref name=pmid24535381>{{Cite journal | last1 = Xu | first1 = ZQ. | last2 = Xie | first2 = LJ. | last3 = Fan | first3 = W. | last4 = Duan | first4 = XB. | last5 = Cheng | first5 = MH. | title = Risk factors for mediastinal lymph node metastasis in non-small-cell lung cancer by PET/CT. | journal = Nucl Med Commun | volume = 35 | issue = 5 | pages = 466-71 | month = May | year = 2014 | doi = 10.1097/MNM.0000000000000077 | PMID = 24535381 }}</ref> | |||
**Cut-off: 9.3. | **Cut-off: 9.3. | ||
***[[Sensitivity]] ~75%. | ***[[Sensitivity]] ~75%. | ||
***[[Specificity]] ~54%. | ***[[Specificity]] ~54%. | ||
*The ratio of the ''SUV node/SUV primary tumour (SUV<sub>N</sub>/SUV<sub>T</sub>)'' is better predictor than the ''maximal (node) SUV (SUV<sub>max</sub>)''.<ref name=pmid26163919>{{Cite journal | last1 = Mattes | first1 = MD. | last2 = Moshchinsky | first2 = AB. | last3 = Ahsanuddin | first3 = S. | last4 = Rizk | first4 = NP. | last5 = Foster | first5 = A. | last6 = Wu | first6 = AJ. | last7 = Ashamalla | first7 = H. | last8 = Weber | first8 = WA. | last9 = Rimner | first9 = A. | title = Ratio of Lymph Node to Primary Tumor SUV on PET/CT Accurately Predicts Nodal Malignancy in Non-Small-Cell Lung Cancer. | journal = Clin Lung Cancer | volume = | issue = | pages = | month = Jun | year = 2015 | doi = 10.1016/j.cllc.2015.06.001 | PMID = 26163919 }}</ref> | |||
**Cut-off: 0.28. | |||
***Sensitivity 90%. | |||
***Specificity 68%. | |||
==See also== | ==See also== | ||
*[[Oncology]]. | *[[Oncology]]. | ||
*[[Positron emission tomography]]. | |||
==References== | |||
{{Reflist|1}} | |||
==External links== | ==External links== | ||
Latest revision as of 15:07, 28 November 2023
Standardized uptake value, abbreviated SUV, is a semi-quantitative measure in PET scans.
Non-small cell lung cancer
Main article: Non-small cell lung cancer
- The SUV of fluorine-18 fluorodeoxyglucose of the primary tumour is a predictor of lymph node metastases in a multivariate analysis.[1]
- Cut-off: 9.3.
- Sensitivity ~75%.
- Specificity ~54%.
- Cut-off: 9.3.
- The ratio of the SUV node/SUV primary tumour (SUVN/SUVT) is better predictor than the maximal (node) SUV (SUVmax).[2]
- Cut-off: 0.28.
- Sensitivity 90%.
- Specificity 68%.
- Cut-off: 0.28.
See also
References
- ↑ Xu, ZQ.; Xie, LJ.; Fan, W.; Duan, XB.; Cheng, MH. (May 2014). "Risk factors for mediastinal lymph node metastasis in non-small-cell lung cancer by PET/CT.". Nucl Med Commun 35 (5): 466-71. doi:10.1097/MNM.0000000000000077. PMID 24535381.
- ↑ Mattes, MD.; Moshchinsky, AB.; Ahsanuddin, S.; Rizk, NP.; Foster, A.; Wu, AJ.; Ashamalla, H.; Weber, WA. et al. (Jun 2015). "Ratio of Lymph Node to Primary Tumor SUV on PET/CT Accurately Predicts Nodal Malignancy in Non-Small-Cell Lung Cancer.". Clin Lung Cancer. doi:10.1016/j.cllc.2015.06.001. PMID 26163919.