Difference between revisions of "Mucinous fibroplasia"

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'''Mucinous fibroplasia''', also '''collagenous micronodules''', is a pathognomonic feature of [[prostate carcinoma]].<ref name=pmid16613324>{{Cite journal  | last1 = Egevad | first1 = L. | last2 = Allsbrook | first2 = WC. | last3 = Epstein | first3 = JI. | title = Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists. | journal = Hum Pathol | volume = 37 | issue = 3 | pages = 292-7 | month = Mar | year = 2006 | doi =  | PMID = 16613324 }}</ref><ref name=pmid10435561>{{Cite journal  | last1 = Baisden | first1 = BL. | last2 = Kahane | first2 = H. | last3 = Epstein | first3 = JI. | title = Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 23 | issue = 8 | pages = 918-24 | month = Aug | year = 1999 | doi =  | PMID = 10435561 }}</ref>
[[Image:Mucinous fibroplasia -- very high mag.jpg|thumb|300px|[[Micrograph]] showing mucinous fibroplasia. [[H&E stain]]. (WC)]]
'''Mucinous fibroplasia''', also '''collagenous micronodules''', is a finding seen in the [[prostate gland]] that is considered pathognomonic for [[prostate carcinoma]] by many genitourinary pathologists.<ref name=pmid16613324>{{Cite journal  | last1 = Egevad | first1 = L. | last2 = Allsbrook | first2 = WC. | last3 = Epstein | first3 = JI. | title = Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists. | journal = Hum Pathol | volume = 37 | issue = 3 | pages = 292-7 | month = Mar | year = 2006 | doi =  | PMID = 16613324 }}</ref><ref name=pmid10435561>{{Cite journal  | last1 = Baisden | first1 = BL. | last2 = Kahane | first2 = H. | last3 = Epstein | first3 = JI. | title = Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 23 | issue = 8 | pages = 918-24 | month = Aug | year = 1999 | doi =  | PMID = 10435561 }}</ref>
 
==General==
*Considered pathognomonic by 64% of genitourinary pathologists in one survey with 64 respondents.<ref name=pmid16613324/>
*Thought to arise from intraglandular mucin.{{fact}}


==Microscopic==
==Microscopic==
Features:
Features:
*Small collegneous-like nodules within (malignant) prostatic glands.
*Small collegneous-like nodules within (malignant) prostatic glands.
===Images===
<gallery>
Image: Mucinous fibroplasia -- high mag.jpg | CM - high mag.
Image: Mucinous fibroplasia -- very high mag.jpg | CM - very high mag.
Image: Mucinous fibroplasia - alt -- very high mag.jpg | CM - very high mag.
</gallery>


==See also==
==See also==

Latest revision as of 04:40, 5 April 2015

Micrograph showing mucinous fibroplasia. H&E stain. (WC)

Mucinous fibroplasia, also collagenous micronodules, is a finding seen in the prostate gland that is considered pathognomonic for prostate carcinoma by many genitourinary pathologists.[1][2]

General

  • Considered pathognomonic by 64% of genitourinary pathologists in one survey with 64 respondents.[1]
  • Thought to arise from intraglandular mucin.[citation needed]

Microscopic

Features:

  • Small collegneous-like nodules within (malignant) prostatic glands.

Images

See also

References

  1. 1.0 1.1 Egevad, L.; Allsbrook, WC.; Epstein, JI. (Mar 2006). "Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists.". Hum Pathol 37 (3): 292-7. PMID 16613324.
  2. Baisden, BL.; Kahane, H.; Epstein, JI. (Aug 1999). "Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy.". Am J Surg Pathol 23 (8): 918-24. PMID 10435561.