Difference between revisions of "Critical values"
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'''Critical values''' is a concept which comes to anatomical pathology from clinical pathology.<ref name=pmid17491125>{{cite journal |author=Allen TC |title=Critical values in anatomic pathology? |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=5 |pages=684–7 |year=2007 |month=May |pmid=17491125 |doi= |url=http://arpa.allenpress.com/arpaonline/?request=get-document&issn=0003-9985&volume=131&issue=5&page=684}}</ref> | [[Image:ECG in hyperkalemia.png | thumb| right|200px| Hyperkalemia is a critical value as it is associated with [[cardiac arrhythmias]].]] | ||
'''Critical values''' is a concept which comes to anatomical [[pathology]] from clinical pathology.<ref name=pmid17491125>{{cite journal |author=Allen TC |title=Critical values in anatomic pathology? |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=5 |pages=684–7 |year=2007 |month=May |pmid=17491125 |doi= |url=http://arpa.allenpress.com/arpaonline/?request=get-document&issn=0003-9985&volume=131&issue=5&page=684}}</ref> | |||
In the context of surgical | In the context of surgical pathology, it is, perhaps more appropriately, called '''critical [[diagnosis]]'''. | ||
The general consensus is that these findings require a phone call and/or discussion with the clinician to ensure the situation is managed appropriately in a timely manner.<ref name=pmid16680772/> | The general consensus is that these findings (critical valves, critical diagnoses) require a phone call and/or discussion with the clinician to ensure the situation is managed appropriately in a timely manner.<ref name=pmid16680772/> | ||
==List of critical diagnoses== | ==List of critical diagnoses== | ||
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====Gynecologic==== | ====Gynecologic==== | ||
* | *D&C on pregnant individual (or specimen labelled "[[products of conception]]") without [[chorionic villi]] or trophoblasts. | ||
*[[Fat on endometrial biopsy]]. | *[[Fat on endometrial biopsy]]. | ||
*Fat on endocervical canal sampling. | *Fat on endocervical canal sampling. | ||
| Line 46: | Line 47: | ||
====Renal==== | ====Renal==== | ||
*[[Glomerular crescents|Crescents]] in kidney biopsy. | *[[Glomerular crescents|Crescents]] in kidney biopsy. | ||
==List of diagnoses that should be reviewed== | |||
*[[AKA]] ''review diagnoses''. | |||
Review diagnoses are diagnoses that have significant treatment implications, and often mandate the opinion of a second pathologist and/or a sub-specialist. There is no general consensus around which diagnoses require review. | |||
Examples of diagnoses that are high impact and are frequently reviewed: | |||
*[[Columnar dysplasia of the esophagus|High grade columnar esophageal dysplasia]].<ref name=pmid9189080>{{Cite journal | last1 = Wright | first1 = TA. | title = High-grade dysplasia in Barrett's oesophagus. | journal = Br J Surg | volume = 84 | issue = 6 | pages = 760-6 | month = Jun | year = 1997 | doi = | PMID = 9189080 }}</ref> | |||
*[[urothelial carcinoma|Muscle invasive urothelial carcinoma of the bladder]].<ref>{{Cite journal | last1 = Coblentz | first1 = TR. | last2 = Mills | first2 = SE. | last3 = Theodorescu | first3 = D. | title = Impact of second opinion pathology in the definitive management of patients with bladder carcinoma. | journal = Cancer | volume = 91 | issue = 7 | pages = 1284-90 | month = Apr | year = 2001 | doi = | PMID = 11283928 }}</ref> | |||
==See also== | ==See also== | ||
*[[Basics]]. | *[[Basics]]. | ||
*[[Quality]]. | *[[Quality]]. | ||
*[[Diagnosis]]. | |||
==References== | ==References== | ||
Latest revision as of 21:09, 4 November 2015
Hyperkalemia is a critical value as it is associated with cardiac arrhythmias.
Critical values is a concept which comes to anatomical pathology from clinical pathology.[1]
In the context of surgical pathology, it is, perhaps more appropriately, called critical diagnosis.
The general consensus is that these findings (critical valves, critical diagnoses) require a phone call and/or discussion with the clinician to ensure the situation is managed appropriately in a timely manner.[2]
List of critical diagnoses
Cytology
Critical diagnoses as per Pereira et al.:[2]
- Unexpected malignancy - vast majority of cases.
- Microorganisms in non-gynecologic specimens and FNA specimens.
Surgical pathology
The following is primarily constructed from a list in Pereira et al.[3]
General
- Large vessel in core biopsy specimen.
- Unexpected malignant diagnosis.
- Malignant diagnosis in the context of a medical emergency:
- Neoplasm causing paralysis.
- Malignancy causing superior vena cava syndrome.
Gynecologic
- D&C on pregnant individual (or specimen labelled "products of conception") without chorionic villi or trophoblasts.
- Fat on endometrial biopsy.
- Fat on endocervical canal sampling.
Diagnostic of infection
- Fungal.
- Microbacterial.
- Bacterial.
- Viral.
Suggestive of infection
- Necrotic granulomas.
Cardiac
- Mesothelial cells in heart muscle biopsy.
- Transplant rejection.
Medical diseases
Renal
- Crescents in kidney biopsy.
List of diagnoses that should be reviewed
- AKA review diagnoses.
Review diagnoses are diagnoses that have significant treatment implications, and often mandate the opinion of a second pathologist and/or a sub-specialist. There is no general consensus around which diagnoses require review.
Examples of diagnoses that are high impact and are frequently reviewed:
- High grade columnar esophageal dysplasia.[4]
- Muscle invasive urothelial carcinoma of the bladder.[5]
See also
References
- ↑ Allen TC (May 2007). "Critical values in anatomic pathology?". Arch. Pathol. Lab. Med. 131 (5): 684–7. PMID 17491125. http://arpa.allenpress.com/arpaonline/?request=get-document&issn=0003-9985&volume=131&issue=5&page=684.
- ↑ 2.0 2.1 Pereira, TC.; Clayton, AC.; Tazelaar, HD.; Liu, Y.; Leon, M.; Silverman, JF. (Jun 2006). "Critical values in cytology.". Diagn Cytopathol 34 (6): 447-51. doi:10.1002/dc.20443. PMID 16680772.
- ↑ Pereira, TC.; Liu, Y.; Silverman, JF. (Aug 2004). "Critical values in surgical pathology.". Am J Clin Pathol 122 (2): 201-5. doi:10.1309/7NRW-7G68-4VEP-WPMR. PMID 15323136.
- ↑ Wright, TA. (Jun 1997). "High-grade dysplasia in Barrett's oesophagus.". Br J Surg 84 (6): 760-6. PMID 9189080.
- ↑ Coblentz, TR.; Mills, SE.; Theodorescu, D. (Apr 2001). "Impact of second opinion pathology in the definitive management of patients with bladder carcinoma.". Cancer 91 (7): 1284-90. PMID 11283928.