Difference between revisions of "Rheumatoid lung nodule"

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#REDIRECT [[Rheumatoid lung disease]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      =
| Width      =
| Caption    =
| Synonyms  =
| Micro      = mixed inflammatory infiltrate, +/-[[giant cells]], no micro-organisms
| Subtypes  =
| LMDDx      = necrotic pulmonary nodules in [[Crohn's disease]], [[infectious pneumonia]], [[amyloidosis]] of lung
| Stains    = ZN -ve, GMS -ve
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[lung]] - see ''[[medical lung diseases]]''
| Assdx      = [[rheumatoid arthritis]]
| Syndromes  =
| Clinicalhx = +/-hx of rheumatoid arthritis
| Signs      =
| Symptoms  =
| Prevalence = uncommon
| Bloodwork  =
| Rads      = upper lung fields, peripheral, round, +/-cavitation
| Endoscopy  =
| Prognosis  =
| Other      =
| ClinDDx    = only lung lesions - esp. malignancy
| Tx        =
}}
'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''' and '''pulmonary rheumatoid nodule''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]].
 
''Rheumatoid lung disease'' redirects here. ''[[Rheumatoid pleuritis]]'' is dealt with separately.
 
==General==
*Rare.<ref name=pmid22265461>{{Cite journal  | last1 = Gómez Herrero | first1 = H. | last2 = Arraiza Sarasa | first2 = M. | last3 = Rubio Marco | first3 = I. | last4 = García de Eulate Martín-Moro | first4 = I. | title = Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases. | journal = Reumatol Clin | volume = 8 | issue = 4 | pages = 212-5 | month =  | year =  | doi = 10.1016/j.reuma.2011.09.004 | PMID = 22265461 }}</ref>
 
Common associations:<ref name=pmid22265461/>
*Male.
*RF +ve.
*Skin nodules - see ''[[rheumatoid nodule]]''.
 
==Gross/radiology==
Features:<ref name=pmid22265461/>
*Usually upper lung fields, peripheral and round.
*+/-Cavitation (~50% of cases).
 
==Microscopic==
Features:<ref name=pmid23984160/>
*Mixed inflammatory infiltrate.
*+/-[[Giant cells]].
*No micro-organisms.
 
Dx:
*Necrotic pulmonary nodule in [[Crohn's disease]].
*[[Infectious pneumonia]].
*[[Amyloidosis]]<ref name=pmid17037396>{{cite journal |authors=Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H |title=Nodular pulmonary amyloidosis |journal=Jpn J Thorac Cardiovasc Surg |volume=54 |issue=9 |pages=399–401 |date=September 2006 |pmid=17037396 |doi=10.1007/s11748-006-0015-4 |url=}}</ref> - reported in the context with rheumatoid arthritis.<ref name=pmid17332981>{{cite journal |authors=Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH |title=Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis |journal=Clin Rheumatol |volume=26 |issue=10 |pages=1797–8 |date=October 2007 |pmid=17332981 |doi=10.1007/s10067-007-0552-y |url=}}</ref>
 
===Images===
www:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741933/figure/fig3/ RLN (nih.gov)].<ref name=pmid23984160/>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741933/figure/fig4/ RLN (nih.gov)].<ref name=pmid23984160>{{Cite journal  | last1 = Chhakchhuak | first1 = CL. | last2 = Khosravi | first2 = M. | last3 = Lohr | first3 = KM. | title = Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature. | journal = Case Rep Rheumatol | volume = 2013 | issue =  | pages = 621340 | month =  | year = 2013 | doi = 10.1155/2013/621340 | PMID = 23984160 }}</ref>
 
==Stains==
*[[ZN stain]] -ve for AFB.
*[[GMS stain]] -ve for [[fungal organisms]].
*[[Congo red]] -ve.
 
==See also==
*[[Medical lung disease]].
*[[Rheumatoid nodule]].
*[[Rheumatoid arthritis]].
 
==References==
{{Reflist|1}}
 
[[Category:Diagnosis]]

Latest revision as of 16:36, 3 March 2022

Rheumatoid lung nodule
Diagnosis in short
LM mixed inflammatory infiltrate, +/-giant cells, no micro-organisms
LM DDx necrotic pulmonary nodules in Crohn's disease, infectious pneumonia, amyloidosis of lung
Stains ZN -ve, GMS -ve
Site lung - see medical lung diseases
Associated Dx rheumatoid arthritis
Clinical history +/-hx of rheumatoid arthritis
Prevalence uncommon
Radiology upper lung fields, peripheral, round, +/-cavitation
Clin. DDx only lung lesions - esp. malignancy

Rheumatoid lung nodule, also rheumatoid nodule of the lung and pulmonary rheumatoid nodule, is an uncommon benign lung lesion associated with rheumatoid arthritis.

Rheumatoid lung disease redirects here. Rheumatoid pleuritis is dealt with separately.

General

Common associations:[1]

Gross/radiology

Features:[1]

  • Usually upper lung fields, peripheral and round.
  • +/-Cavitation (~50% of cases).

Microscopic

Features:[2]

  • Mixed inflammatory infiltrate.
  • +/-Giant cells.
  • No micro-organisms.

Dx:

Images

www:

Stains

See also

References

  1. ↑ 1.0 1.1 1.2 Gómez Herrero, H.; Arraiza Sarasa, M.; Rubio Marco, I.; García de Eulate Martín-Moro, I.. "Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases.". Reumatol Clin 8 (4): 212-5. doi:10.1016/j.reuma.2011.09.004. PMID 22265461.
  2. ↑ 2.0 2.1 2.2 Chhakchhuak, CL.; Khosravi, M.; Lohr, KM. (2013). "Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature.". Case Rep Rheumatol 2013: 621340. doi:10.1155/2013/621340. PMID 23984160.
  3. ↑ Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H (September 2006). "Nodular pulmonary amyloidosis". Jpn J Thorac Cardiovasc Surg 54 (9): 399–401. doi:10.1007/s11748-006-0015-4. PMID 17037396.
  4. ↑ Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH (October 2007). "Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis". Clin Rheumatol 26 (10): 1797–8. doi:10.1007/s10067-007-0552-y. PMID 17332981.
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