Difference between revisions of "Case 69"
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Low magnification. H&E stain.
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===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>[[Benign Toker cell hyperplasia]], [[Malignant melanoma]], [[Paget disease of the breast]], [[Eccrine carcinoma]], [[Squamous cell carcinoma of the skin]]</center>}} | {{hidden|Differential diagnosis|<center>[[Benign Toker cell hyperplasia]], [[Malignant melanoma]], [[Paget disease of the breast]], [[Eccrine carcinoma]], [[Bowen disease]], [[Squamous cell carcinoma of the skin]]</center>}} | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center> | {{hidden|More history|<center>The patient spends the majority of the day every day out doors</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>This is the early stage of a malignant lesion</center>}} | ||
====Stains==== | ====Stains==== | ||
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| cd99= | | cd99= | ||
| cdx2= | | cdx2= | ||
| cea= | | cea= -ve | ||
| chromo= | | chromo= | ||
| chromo= | | chromo= | ||
| Line 123: | Line 123: | ||
| ck20= | | ck20= | ||
| ck34be12= | | ck34be12= | ||
| ck5_6= | | ck5_6= +ve | ||
| ck7= | | ck7= -ve | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
| Line 153: | Line 153: | ||
| her2= | | her2= | ||
| hhv8= | | hhv8= | ||
| hmb45= | | hmb45= -ve | ||
| hnf1beta= | | hnf1beta= | ||
| hpv= | | hpv= +ve | ||
| hsv1= | | hsv1= | ||
| hsv2= | | hsv2= | ||
| Line 183: | Line 183: | ||
| oct3_4= | | oct3_4= | ||
| p16= | | p16= | ||
| p53= | | p53= +ve | ||
| p57= | | p57= | ||
| p63= | | p63= | ||
| Line 198: | Line 198: | ||
| psap= | | psap= | ||
| rcc= | | rcc= | ||
| s100= | | s100= -ve | ||
| sma= | | sma= | ||
| somatsatin= | | somatsatin= | ||
| Line 242: | Line 242: | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center> | {{hidden|Diagnosis|<center>[[Bowen disease]]</center>}} | ||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
{{Cases navigation}} | {{Cases navigation}} | ||
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[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in dermatopathology]] | |||
[[Category:Cases in | [[Category:Cases in dermatopathology - junior]] | ||
[[Category:Cases difficulty | [[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | ||
Latest revision as of 12:58, 2 July 2014
Provided clinical history
69 year old man, fisherman of 50 years, skin lesion
Site
Back, 1 cm x 1 cm lesion
Primary image
Intermediate magnification
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High magnification
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Differential diagnosis
Differential diagnosis
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Chromosomal translocations
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Diagnosis
Diagnosis
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