Talk:Neuropathology tumours: Difference between revisions
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→Pilocytic astrocytoma: new section |
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===Final diagnosis=== | ===Final diagnosis=== | ||
BRAIN, CEREBELLUM, EXCISION: | BRAIN, CEREBELLUM, EXCISION: | ||
<br> - HEMANGIOBLASTOMA. | <br> - HEMANGIOBLASTOMA (WHO GRADE I). | ||
==Metastatic large cell carcinoma== | ==Metastatic large cell carcinoma== | ||
| Line 51: | Line 51: | ||
NERVE, LEFT RADIAL: | NERVE, LEFT RADIAL: | ||
<Br>- TRAUMATIC NEUROMA. | <Br>- TRAUMATIC NEUROMA. | ||
== Chordoma == | |||
===Microscopic description=== | |||
The sections show a tumour composed of irregular anatoming cords of physaliferous cells resting on a myxoid background. Mitotic activity is not detected. | |||
Immunostains demonstrate that the tumour cells intensely express cytoplasmic for low molecular weight keratin (LMWCK) and membranous epithelial membrane antigen (EMA). There is weak, focal cytoplasmic expression of S100. | |||
===Final diagnosis=== | |||
CLIVUS: | |||
<br>- CHORDOMA. | |||
== Pilocytic astrocytoma == | |||
===Microscopic description=== | |||
The smear shows bipolar cells with thick hair-like processes. The sections show a cellular tumour with eosinophilic cytoplasm drawn into processes. Eosinophilic granular bodies and Rosenthal fibres are present, as demonstrated with trichrome staining. | |||
There is no nuclear pleomorphism and no mitotic activity. There is no microvascular proliferation and no necrosis. | |||
===Final diagnosis=== | |||
BRAIN:<br> | |||
- PILOCYTIC ASTROCYTOMA (WHO GRADE I). | |||