Difference between revisions of "Insular thyroid carcinoma"
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'''Insular thyroid carcinoma''', also '''insular carcinoma''', is a rare clinically aggressive form of [[thyroid | '''Insular thyroid carcinoma''', also '''insular carcinoma''', is a rare clinically aggressive form of [[thyroid gland|thyroid]] carcinoma.<ref>{{cite journal |author=Hod R, Bachar G, Sternov Y, Shvero J |title=Insular thyroid carcinoma: a retrospective clinicopathologic study |journal=Am J Otolaryngol |volume=34 |issue=4 |pages=292–5 |year=2013 |pmid=23357591 |doi=10.1016/j.amjoto.2012.12.009 |url=}}</ref> | ||
It may be lumped with [[papillary thyroid carcinoma]]. | It may be lumped with [[papillary thyroid carcinoma]]. | ||
Latest revision as of 14:37, 30 May 2014
Insular thyroid carcinoma, also insular carcinoma, is a rare clinically aggressive form of thyroid carcinoma.[1]
It may be lumped with papillary thyroid carcinoma.
General
Features:[2]
- Rare - approximately 5% of all thyroid carcinomas.
- Thought to be a separate tumour from papillary thyroid carcinoma and follicular thyroid carcinoma with a focal insular pattern.
- Some lump this entity with papillary carcinoma, i.e. consider it a variant of papillary thyroid carcinoma.
Microscopic
Features:[2]
- Islands of cells - key feature.
- Scant cytoplasm.
- Nuclei monomorphic and round.
DDx:[3]
- Medullary thyroid carcinoma.
- Poorly differentiated thyroid carcinoma.
Images
www:
See also
References
- ↑ Hod R, Bachar G, Sternov Y, Shvero J (2013). "Insular thyroid carcinoma: a retrospective clinicopathologic study". Am J Otolaryngol 34 (4): 292–5. doi:10.1016/j.amjoto.2012.12.009. PMID 23357591.
- ↑ 2.0 2.1 Rufini V, Salvatori M, Fadda G, et al. (September 2007). "Thyroid carcinomas with a variable insular component: prognostic significance of histopathologic patterns". Cancer 110 (6): 1209–17. doi:10.1002/cncr.22913. PMID 17665497.
- ↑ Endo. fellow. 17 September 2009.