Difference between revisions of "Oral contraceptive pill"

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[[Image:Pillpacketopen.jpg|thumb|right|250px|OCP package.]]
[[Image:Pillpacketopen.jpg|thumb|right|250px|OCP package.]]
The '''oral contraceptive pill''', abbreviated '''OCP''', is a widely used form of birth control that may result in distinctive histomorphologic changes.
The '''oral contraceptive pill''', abbreviated '''OCP''', is a widely used form of birth control that may result in distinctive histomorphologic changes.  


==General==
==General==
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==Bengin histomorphologic changes==
==Bengin histomorphologic changes==
[[Image:Endometrium_with_hormone_effect_--_intermed_mag.jpg|thumb|right|200px|[[Endometrial changes of oral contraception]]. [[H&E stain]]. (WC)]]
*[[Endometrial changes of oral contraception]].
*[[Endometrial changes of oral contraception]].
*[[Microglandular hyperplasia]].<ref name=pmid10757337>{{Cite journal  | last1 = Zaino | first1 = RJ. | title = Glandular lesions of the uterine cervix. | journal = Mod Pathol | volume = 13 | issue = 3 | pages = 261-74 | month = Mar | year = 2000 | doi = 10.1038/modpathol.3880047 | PMID = 10757337 | URL = http://www.nature.com/modpathol/journal/v13/n3/full/3880047a.html }}</ref>
*[[Microglandular hyperplasia]].<ref name=pmid10757337>{{Cite journal  | last1 = Zaino | first1 = RJ. | title = Glandular lesions of the uterine cervix. | journal = Mod Pathol | volume = 13 | issue = 3 | pages = 261-74 | month = Mar | year = 2000 | doi = 10.1038/modpathol.3880047 | PMID = 10757337 | URL = http://www.nature.com/modpathol/journal/v13/n3/full/3880047a.html }}</ref>
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==Associated pathology==
==Associated pathology==
*[[Hepatic adenoma]].<ref name=Ref_WMSP221>{{Ref WMSP|221}}</ref><ref name=pmid221698>{{Cite journal  | last1 = Rooks | first1 = JB. | last2 = Ory | first2 = HW. | last3 = Ishak | first3 = KG. | last4 = Strauss | first4 = LT. | last5 = Greenspan | first5 = JR. | last6 = Hill | first6 = AP. | last7 = Tyler | first7 = CW. | title = Epidemiology of hepatocellular adenoma. The role of oral contraceptive use. | journal = JAMA | volume = 242 | issue = 7 | pages = 644-8 | month = Aug | year = 1979 | doi =  | PMID = 221698 }}</ref>
*[[Hepatic adenoma]].<ref name=Ref_WMSP221>{{Ref WMSP|221}}</ref><ref name=pmid221698>{{Cite journal  | last1 = Rooks | first1 = JB. | last2 = Ory | first2 = HW. | last3 = Ishak | first3 = KG. | last4 = Strauss | first4 = LT. | last5 = Greenspan | first5 = JR. | last6 = Hill | first6 = AP. | last7 = Tyler | first7 = CW. | title = Epidemiology of hepatocellular adenoma. The role of oral contraceptive use. | journal = JAMA | volume = 242 | issue = 7 | pages = 644-8 | month = Aug | year = 1979 | doi =  | PMID = 221698 }}</ref>
*[[Epithelioid hemangioendothelioma]].<ref name=pmid20165548>{{Cite journal  | last1 = Gupta | first1 = R. | last2 = Mathur | first2 = SR. | last3 = Gupta | first3 = SD. | last4 = Durgapal | first4 = P. | last5 = Iyer | first5 = VK. | last6 = Das | first6 = CJ. | last7 = Shalimar | first7 = SK. | last8 = Acharya | first8 = . | title = Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology. | journal = Cytojournal | volume = 6 | issue =  | pages = 25 | month =  | year = 2010 | doi = 10.4103/1742-6413.58951 | PMID = 20165548 }}</ref>


==See also==
==See also==
*[[Drug reaction]].
*[[Drug reaction]].
*[[Clinical history]].
*[[Clinical history]].
*[[Intrauterine device]].


==References==
==References==
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[[Category:Gynecologic pathology]]
[[Category:Gynecologic pathology]]
[[Category:Drugs]]

Latest revision as of 14:20, 27 November 2015

OCP package.

The oral contraceptive pill, abbreviated OCP, is a widely used form of birth control that may result in distinctive histomorphologic changes.

General

Contraindications

Mnemonic ABBCCCD:[1][2]

  • Acute or chronic liver disease (e.g. Wilson's disease).
  • Bad migraines (with focal neurological signs).
  • Bleed per vagina - undiagnosed.
  • Cancer (endometrial, breast).
  • Cardiovascular disease.
  • Cardiovascular disease risk factors.
    • Smoking >35 years.
    • Uncontrolled BP.
  • DVT.
  • Suspected pregnancy.

Advantages of use

Mnemonic AABCDE:[1][2]

  • Acne reduced, Anemia reduced.
  • Benign breast disease reduced.
  • Cancer reduced (ovary, endometrium).
  • Dysmenorrhea Sx better.
  • Endometriosis Sx better.
  • Pregnancy prevention.

Bengin histomorphologic changes

Associated pathology

See also

References

  1. 1.0 1.1 Yeung, J.C.; Leonard, Blair J. N. (2005). The Toronto Notes 2005 - Review for the MCCQE and Comprehensive Medical Reference (2005 ed.). The Toronto Notes Inc. for Medical Students Inc.. pp. FM44. ISBN 978-0968592854.
  2. 2.0 2.1 Shiau, Carolyn; Toren, Andrew (2006). Toronto Notes 2006: Comprehensive Medical Reference (Review for MCCQE 1 and USMLE Step 2) (22nd edition (2006) ed.). Toronto Notes for Medical Students, Inc.. pp. GY20. ISBN 978-0968592861.
  3. Zaino, RJ. (Mar 2000). "Glandular lesions of the uterine cervix.". Mod Pathol 13 (3): 261-74. doi:10.1038/modpathol.3880047. PMID 10757337.
  4. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 221. ISBN 978-0781765275.
  5. Rooks, JB.; Ory, HW.; Ishak, KG.; Strauss, LT.; Greenspan, JR.; Hill, AP.; Tyler, CW. (Aug 1979). "Epidemiology of hepatocellular adenoma. The role of oral contraceptive use.". JAMA 242 (7): 644-8. PMID 221698.
  6. Gupta, R.; Mathur, SR.; Gupta, SD.; Durgapal, P.; Iyer, VK.; Das, CJ.; Shalimar, SK.; Acharya, . (2010). "Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology.". Cytojournal 6: 25. doi:10.4103/1742-6413.58951. PMID 20165548.