Difference between revisions of "Histology artifacts"

From Libre Pathology
Jump to navigation Jump to search
 
(6 intermediate revisions by the same user not shown)
Line 7: Line 7:
*Darker well demarcated line with apparent disruption of the architecture.
*Darker well demarcated line with apparent disruption of the architecture.


===Images===
<gallery>
<gallery>
Image:Basal cell hyperplasia of the prostate -- high mag.jpg | Tissue fold (center of image) in [[basal cell hyperplasia of the prostate]].  
Image:Basal cell hyperplasia of the prostate -- high mag.jpg | Tissue fold (center of image) in [[basal cell hyperplasia of the prostate]].  
Line 15: Line 16:
*Fine parallel lines.
*Fine parallel lines.


===Images===
<gallery>
<gallery>
Image:Tubular_adenoma_2_high_mag.jpg | Chatter artifact in [[traditional adenoma|tubular adenoma]].
Image:Tubular_adenoma_2_high_mag.jpg | Chatter artifact in [[traditional adenoma|tubular adenoma]].
Line 24: Line 26:
*Usually due to something intrinsic to the tissue that is hard, e.g. calcium.
*Usually due to something intrinsic to the tissue that is hard, e.g. calcium.


===Image===
<gallery>
<gallery>
Image:Tooth_in_teratoma_-_very_low_mag.jpg | Tearing due to a calcification.
Image:Tooth_in_teratoma_-_very_low_mag.jpg | Tearing due to a calcification.
Line 29: Line 32:


==Sponge artifact==
==Sponge artifact==
*Little squares of tissue in a regular pattern.
*Angulated pieces of tissue with punched-out missing fragments.<ref name=pmid2252429>{{cite journal |author=Landas SK, Bromley CM |title=Sponge artifact in biopsy specimens |journal=Arch. Pathol. Lab. Med. |volume=114 |issue=12 |pages=1285–7 |year=1990 |month=December |pmid=2252429 |doi= |url=}}</ref>
*May result in little squares of tissue arranged in a regular pattern.
 
===Images===
<gallery>
Image: Endometrium with sponge artifact -- very low mag.jpg | Sponge artifact - very low mag.
Image: Endometrium with sponge artifact -- low mag.jpg | Sponge artifact - low mag.
Image: Endometrium with sponge artifact -- intermed mag.jpg | Sponge artifact - intermed. mag.
</gallery>


==Bubble artifact==
==Bubble artifact==
===Large===
===Large===
*Large bubbles of air under the cover slip.
*Large bubbles of air under the cover slip.
====Images====
<gallery>
Image: Coverslip artifact -- intermed mag.jpg | CA - intermed. mag. (WC)
Image: Coverslip artifact -- high mag.jpg | CA - high mag. (WC)
Image: Coverslip artifact - alt -- high mag.jpg | CA - high mag. (WC)
</gallery>


==Coverslip artifact==
==Coverslip artifact==
Line 40: Line 58:
*Above the plane-of-focus of the tissue - '''key feature'''.
*Above the plane-of-focus of the tissue - '''key feature'''.


Image:
===Images===
*[http://www.statvetlab.com/images/uploads/diagnostic_resources/30/ua_artifact_cover_slip_2__large.jpg Coverlip artifact (statvetlab.com)].<ref>URL: [http://www.statvetlab.com/diagnostic-resources/urinalysis http://www.statvetlab.com/diagnostic-resources/urinalysis]. Accessed on: 3 March 2014.</ref>
====Case 1====
<gallery>
Image: Epididymis with coverslip artifact -- low mag.jpg | CSA - low mag. (WC)
Image: Epididymis with coverslip artifact -- intermed mag.jpg | CSA - intermed mag. (WC)
Image: Epididymis with coverslip artifact -- high mag.jpg | CSA - high mag. (WC)
Image: Epididymis with coverslip artifact - wc -- high mag.jpg | CSA - high mag. (WC)
Image: Epididymis with coverslip artifact - wc -- very high mag.jpg | CSA - very high mag. (WC)
</gallery>


==See also==
==See also==
Line 47: Line 72:
*[[Tissue floater]].
*[[Tissue floater]].
*[[Quality]].
*[[Quality]].
*[[Foreign material]].


==References==
==References==

Latest revision as of 16:21, 3 January 2020

Histology artifacts are common.

Cautery artifact

Tissue fold

  • Darker well demarcated line with apparent disruption of the architecture.

Images

Chatter artifact

  • Fine parallel lines.

Images

Tissue tearing

  • Usually due to something intrinsic to the tissue that is hard, e.g. calcium.

Image

Sponge artifact

  • Angulated pieces of tissue with punched-out missing fragments.[1]
  • May result in little squares of tissue arranged in a regular pattern.

Images

Bubble artifact

Large

  • Large bubbles of air under the cover slip.

Images

Coverslip artifact

Features:

  • Black-grey lines - takes on the outline of the tissue beneath it.
  • Above the plane-of-focus of the tissue - key feature.

Images

Case 1

See also

References

  1. Landas SK, Bromley CM (December 1990). "Sponge artifact in biopsy specimens". Arch. Pathol. Lab. Med. 114 (12): 1285–7. PMID 2252429.

External links